Heart failure, chronic diuretic use, and increase in mortality and hospitalization: an observational study using propensity score methods

A Ahmed; A Husain; Te Love; Giovanni Gambassi; Lj Dell'Italia; Gs Francis; M Gheorghiade; Rm Allman; S Meleth; Rc Bourge

doi:10.1093/eurheartj/ehi890

Heart failure, chronic diuretic use, and increase in mortality and hospitalization: an observational study using propensity score methods

A Ahmed
, A Husain
, Te Love
, Giovanni Gambassi
, Lj Dell'Italia
, Gs Francis
, M Gheorghiade
, Rm Allman
, S Meleth
, Rc Bourge

Research output: Contribution to journal › Article

323 Citations (Scopus)

Abstract

Non-potassium-sparing diuretics are commonly used in heart failure (HF). They activate the neurohormonal system, and are potentially harmful. Yet, the long-term effects of chronic diuretic use in HF are largely unknown. We retrospectively analysed the Digitalis Investigation Group (DIG) data to determine the effects of diuretics on HF outcomes.

Original language	English
Pages (from-to)	1431-1439
Number of pages	9
Journal	European Heart Journal
Volume	27
Issue number	12
DOIs	https://doi.org/10.1093/eurheartj/ehi890
Publication status	Published - 2006

Keywords

80 and over
Adult
Aged
Ambulatory Care
Cardiotonic Agents
Chronic Disease
Digoxin
Diuretics
Female
Heart Failure
Hospitalization
Humans
Male
Middle Aged
Prognosis
Regression Analysis
Retrospective Studies

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10.1093/eurheartj/ehi890

Cite this

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title = "Heart failure, chronic diuretic use, and increase in mortality and hospitalization: an observational study using propensity score methods",

abstract = "Non-potassium-sparing diuretics are commonly used in heart failure (HF). They activate the neurohormonal system, and are potentially harmful. Yet, the long-term effects of chronic diuretic use in HF are largely unknown. We retrospectively analysed the Digitalis Investigation Group (DIG) data to determine the effects of diuretics on HF outcomes.",

keywords = "80 and over, Adult, Aged, Ambulatory Care, Cardiotonic Agents, Chronic Disease, Digoxin, Diuretics, Female, Heart Failure, Hospitalization, Humans, Male, Middle Aged, Prognosis, Regression Analysis, Retrospective Studies, 80 and over, Adult, Aged, Ambulatory Care, Cardiotonic Agents, Chronic Disease, Digoxin, Diuretics, Female, Heart Failure, Hospitalization, Humans, Male, Middle Aged, Prognosis, Regression Analysis, Retrospective Studies",

author = "A Ahmed and A Husain and Te Love and Giovanni Gambassi and Lj Dell'Italia and Gs Francis and M Gheorghiade and Rm Allman and S Meleth and Rc Bourge",

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doi = "10.1093/eurheartj/ehi890",

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journal = "European Heart Journal",

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TY - JOUR

T1 - Heart failure, chronic diuretic use, and increase in mortality and hospitalization: an observational study using propensity score methods

AU - Ahmed, A

AU - Husain, A

AU - Love, Te

AU - Gambassi, Giovanni

AU - Dell'Italia, Lj

AU - Francis, Gs

AU - Gheorghiade, M

AU - Allman, Rm

AU - Meleth, S

AU - Bourge, Rc

PY - 2006

Y1 - 2006

N2 - Non-potassium-sparing diuretics are commonly used in heart failure (HF). They activate the neurohormonal system, and are potentially harmful. Yet, the long-term effects of chronic diuretic use in HF are largely unknown. We retrospectively analysed the Digitalis Investigation Group (DIG) data to determine the effects of diuretics on HF outcomes.

AB - Non-potassium-sparing diuretics are commonly used in heart failure (HF). They activate the neurohormonal system, and are potentially harmful. Yet, the long-term effects of chronic diuretic use in HF are largely unknown. We retrospectively analysed the Digitalis Investigation Group (DIG) data to determine the effects of diuretics on HF outcomes.

KW - 80 and over

KW - Adult

KW - Aged

KW - Ambulatory Care

KW - Cardiotonic Agents

KW - Chronic Disease

KW - Digoxin

KW - Diuretics

KW - Female

KW - Heart Failure

KW - Hospitalization

KW - Humans

KW - Male

KW - Middle Aged

KW - Prognosis

KW - Regression Analysis

KW - Retrospective Studies

KW - 80 and over

KW - Adult

KW - Aged

KW - Ambulatory Care

KW - Cardiotonic Agents

KW - Chronic Disease

KW - Digoxin

KW - Diuretics

KW - Female

KW - Heart Failure

KW - Hospitalization

KW - Humans

KW - Male

KW - Middle Aged

KW - Prognosis

KW - Regression Analysis

KW - Retrospective Studies

UR - https://publicatt.unicatt.it/handle/10807/37388

U2 - 10.1093/eurheartj/ehi890

DO - 10.1093/eurheartj/ehi890

M3 - Article

SN - 0195-668X

VL - 27

SP - 1431

EP - 1439

JO - European Heart Journal

JF - European Heart Journal

IS - 12

ER -

Heart failure, chronic diuretic use, and increase in mortality and hospitalization: an observational study using propensity score methods

Abstract

Keywords

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