Heart failure, chronic diuretic use, and increase in mortality and hospitalization: an observational study using propensity score methods

A Ahmed, A Husain, Te Love, Giovanni Gambassi, Lj Dell'Italia, Gs Francis, M Gheorghiade, Rm Allman, S Meleth, Rc Bourge

Research output: Contribution to journalArticle

323 Citations (Scopus)

Abstract

Non-potassium-sparing diuretics are commonly used in heart failure (HF). They activate the neurohormonal system, and are potentially harmful. Yet, the long-term effects of chronic diuretic use in HF are largely unknown. We retrospectively analysed the Digitalis Investigation Group (DIG) data to determine the effects of diuretics on HF outcomes.
Original languageEnglish
Pages (from-to)1431-1439
Number of pages9
JournalEuropean Heart Journal
Volume27
DOIs
Publication statusPublished - 2006

Keywords

  • Adult
  • Aged
  • Aged, 80 and over
  • Ambulatory Care
  • Cardiotonic Agents
  • Chronic Disease
  • Digoxin
  • Diuretics
  • Female
  • Heart Failure
  • Hospitalization
  • Humans
  • Male
  • Middle Aged
  • Prognosis
  • Regression Analysis
  • Retrospective Studies

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