Haemophagocytic syndrome associated with mucormycosis infection

Vincenzo Arena, Giuseppe Vetrugno, Raffaele Manna, N. Milic, L. Abenavoli

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2 Citations (Scopus)


Several clinical forms of mucormycosis are recognized. The tendency of mucoraceous zygomycetes to invade the blood vessels often produces a disseminated infection. A case of disseminate mucormycosis complicated by a haemophagocytic syndrome (HS) in a 32-year-old Caucasian male is reported in this article. Few cases of infection-associated HS (IAHS), involving infections caused by fungi, have been reported. In all the recorded cases, the fungal infection coexists with malignant lymphoma, immunodeficiency and a long-term steroid therapy for renal transplant or Crohn's disease. This is the second described case of the HS due to mucormycosis.
Original languageEnglish
Pages (from-to)751-755
Number of pages5
JournalInternational Journal of Immunopathology and Pharmacology
Publication statusPublished - 2012


  • Adult
  • Autopsy
  • Biopsy
  • Bone Marrow Examination
  • Fatal Outcome
  • Gastric Mucosa
  • Humans
  • Immunosuppressive Agents
  • Liver
  • Lymphohistiocytosis, Hemophagocytic
  • Male
  • Mucormycosis
  • Predictive Value of Tests
  • Treatment Outcome


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