Gynecological cancer among adolescents and young adults (AYA)

Stefano Mastrangelo, Palma Maurizi, Antonio Ruggiero, Giorgio Attina', Silvia Triarico, Michele Antonio Capozza

Research output: Contribution to journalArticlepeer-review


Adolescents and young adults (AYA) patients with cancer show specific biological, sociodemographic and behavioral features, with lower survival rates than younger group. Gynecologic malignancies that occur among AYA requires a multidisciplinary management and a tailored model of care, in order to enhance the early diagnosis, the adherence to the treatment, the enrollment in clinical trials, the rate of survival and the quality of life (QoL). In this article, we review the main gynecological tumors that may occur in AYA, with a focus on the clinical signs at the diagnosis and the modality of treatment. In addition, we proposed a model of multidisciplinary and personalized care for AYA with gynecological tumors, which can help the clinicians to manage the specific gynecologic concerns, such as ovarian failure, contraception, fertility, late psychosocial effects.
Original languageEnglish
Pages (from-to)397-397
Number of pages1
JournalAnnals of Translational Medicine
Publication statusPublished - 2020


  • Adolescents and young adults (AYA)
  • gynecologic tumors
  • gynecological concerns
  • oncofertility strategies
  • personalized care


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