Ginsenosides, catechins, quercetin and gut microbiota: Current evidence of challenging interactions

Rosaria Santangelo; Andrea Silvestrini; Cesare Mancuso

doi:10.1016/j.fct.2018.10.042

Ginsenosides, catechins, quercetin and gut microbiota: Current evidence of challenging interactions

Rosaria Santangelo, Andrea Silvestrini, Cesare Mancuso^*

^*Corresponding author

Research output: Contribution to journal › Article › peer-review

35 Citations (Scopus)

Abstract

Recent studies have shown the role of gut microbiota in favoring the absorption of herbal products and the transformation of their active principles into metabolites endowed with biological activity. This review focuses on the evidence supporting the changes occurring, after metabolic reactions by specific bacteria that colonize the human gut, to ginseng-derived ginsenosides, green tea-derived catechins, and quercetin, this latter being a flavonoid aglycon bound to sugars and abundant in some vegetables and roots. Furthermore, the results of several studies demonstrating the potential beneficial effects of the active metabolites generated by these biotransformations on ginsenosides, catechins and quercetin will be reported.

Original language	English
Pages (from-to)	42-49
Number of pages	8
Journal	Food and Chemical Toxicology
Volume	123
DOIs	https://doi.org/10.1016/j.fct.2018.10.042
Publication status	Published - 2019

Keywords

Biotransformation
Catechins
Ginsenosides
Microflora
Personalized nutrition
Quercetin

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10.1016/j.fct.2018.10.042

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title = "Ginsenosides, catechins, quercetin and gut microbiota: Current evidence of challenging interactions",

abstract = "Recent studies have shown the role of gut microbiota in favoring the absorption of herbal products and the transformation of their active principles into metabolites endowed with biological activity. This review focuses on the evidence supporting the changes occurring, after metabolic reactions by specific bacteria that colonize the human gut, to ginseng-derived ginsenosides, green tea-derived catechins, and quercetin, this latter being a flavonoid aglycon bound to sugars and abundant in some vegetables and roots. Furthermore, the results of several studies demonstrating the potential beneficial effects of the active metabolites generated by these biotransformations on ginsenosides, catechins and quercetin will be reported.",

keywords = "Biotransformation, Catechins, Ginsenosides, Microflora, Personalized nutrition, Quercetin, Biotransformation, Catechins, Ginsenosides, Microflora, Personalized nutrition, Quercetin",

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language = "English",

volume = "123",

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TY - JOUR

T1 - Ginsenosides, catechins, quercetin and gut microbiota: Current evidence of challenging interactions

AU - Santangelo, Rosaria

AU - Silvestrini, Andrea

AU - Mancuso, Cesare

PY - 2019

Y1 - 2019

N2 - Recent studies have shown the role of gut microbiota in favoring the absorption of herbal products and the transformation of their active principles into metabolites endowed with biological activity. This review focuses on the evidence supporting the changes occurring, after metabolic reactions by specific bacteria that colonize the human gut, to ginseng-derived ginsenosides, green tea-derived catechins, and quercetin, this latter being a flavonoid aglycon bound to sugars and abundant in some vegetables and roots. Furthermore, the results of several studies demonstrating the potential beneficial effects of the active metabolites generated by these biotransformations on ginsenosides, catechins and quercetin will be reported.

AB - Recent studies have shown the role of gut microbiota in favoring the absorption of herbal products and the transformation of their active principles into metabolites endowed with biological activity. This review focuses on the evidence supporting the changes occurring, after metabolic reactions by specific bacteria that colonize the human gut, to ginseng-derived ginsenosides, green tea-derived catechins, and quercetin, this latter being a flavonoid aglycon bound to sugars and abundant in some vegetables and roots. Furthermore, the results of several studies demonstrating the potential beneficial effects of the active metabolites generated by these biotransformations on ginsenosides, catechins and quercetin will be reported.

KW - Biotransformation

KW - Catechins

KW - Ginsenosides

KW - Microflora

KW - Personalized nutrition

KW - Quercetin

KW - Biotransformation

KW - Catechins

KW - Ginsenosides

KW - Microflora

KW - Personalized nutrition

KW - Quercetin

UR - http://hdl.handle.net/10807/128847

UR - http://www.elsevier.com/locate/foodchemtox

U2 - 10.1016/j.fct.2018.10.042

DO - 10.1016/j.fct.2018.10.042

M3 - Article

SN - 0278-6915

VL - 123

SP - 42

EP - 49

JO - Food and Chemical Toxicology

JF - Food and Chemical Toxicology

ER -

Ginsenosides, catechins, quercetin and gut microbiota: Current evidence of challenging interactions

Abstract

Keywords

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