Genetic diversity of sheep breeds from Albania, Greece, and Italy assessed by mitochondrial DNA and nuclear polymorphisms (SNPs)

Riccardo Negrini, Paolo Ajmone Marsan, Lorraine Pariset, Marco Mariotti, Maria Gargani, Stephane Joost, Trinidad Perez, Michael Bruford, Alessio Valentini

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)

Abstract

We employed mtDNA and nuclear SNPs to investigate the genetic diversity of sheep breeds of three countries of the Mediterranean basin: Albania, Greece, and Italy. In total, 154 unique mtDNA haplotypes were detected by means of D-loop sequence analysis. The major nucleotide diversity was observed in Albania. We identified haplogroups, A, B, and C in Albanian and Greek samples, while Italian individuals clustered in groups A and B. In general, the data show a pattern reflecting old migrations that occurred in postneolithic and historical times. PCA analysis on SNP data differentiated breeds with good correspondence to geographical locations. This could reflect geographical isolation, selection operated by local sheep farmers, and different flock management and breed admixture that occurred in the last centuries.
Original languageEnglish
Pages (from-to)1641-1659
Number of pages19
JournalThe Scientific World Journal
Volume11
DOIs
Publication statusPublished - 2011

Keywords

  • Albania
  • Animals
  • DNA, Mitochondrial
  • Genetic Variation
  • Greece
  • Haplotypes
  • Italy
  • Polymorphism, Single Nucleotide
  • Principal Component Analysis
  • Sheep

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