Functionalized 2,3-dihydrofurans via palladium-catalyzed oxyarylation of α-allyl-β-ketoesters

Sandro Cacchi*, Giancarlo Fabrizi, Antonella Goggiamani, Antonia Iazzetti, David Madec, Giovanni Poli, Guillaume Prestat

*Corresponding author

Research output: Contribution to journalArticle

Abstract

The palladium-catalyzed reaction of (hetero)aryl bromides, chlorides, and nonaflates with α-allyl-β-ketoesters provides ready efficient access to functionalized 2,3-dihydrofurans. The reaction tolerates several useful substituents including chloro, fluoro, ether, ketone, ester, cyano, and nitro groups. © The Royal Society of Chemistry 2011.
Original languageEnglish
Pages (from-to)8233-8236
Number of pages4
JournalORGANIC & BIOMOLECULAR CHEMISTRY
Volume9
DOIs
Publication statusPublished - 2011

Keywords

  • Catalysis
  • Esters
  • Furans
  • Ketones
  • Molecular Structure
  • Palladium
  • Stereoisomerism

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