Functional and structural correlates of persistent ST elevation after acute myocardial infarction successfully treated by percutaneous coronary intervention

Leonarda Galiuto, Gaetano Antonio Lanza, Filippo Crea, Sabrina Barchetta, Antonio Giuseppe Rebuzzi, Serena Paladini, Mario Marzilli

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)

Abstract

Background: In the thrombolytic era, persistence of ST-segment elevation was considered a marker of LV aneurysm. ST-segment elevation may still be found persistently elevated after successful primary PCI. Echocardiographic correlates of this finding, however, are still poorly known. Methods and Results: Eighty-two consecutive patients with first STEMI and successful PCI were divided in patients with persistent ST- segment elevation at discharge (sum of ST > 4 mm) (n=33) and without persistent ST- segment elevation (n=49). Conventional and myocardial contrast echocardiography (MCE) were performed at discharge and at 6 months. At discharge, LV aneurysm was more frequent in persistent ST-elevation patients (30%, p<0.005). Similarly, WMSI was higher (p<0.005) and microvascular damage larger (p<0.005) in patients with persistent ST-segment elevation. At 6 months follow-up, LV volumes were similar in the two groups. Conclusions: After primary PCI, persistent ST-segment elevation is associated with LV aneurysm formation in 30% of cases, it is not associated with significantly larger LV dilation but with larger microvascular damage and dysfunctioning risk area
Original languageEnglish
Pages (from-to)1376-1380
Number of pages5
JournalHeart
Publication statusPublished - 2007

Keywords

  • AMI
  • ST elevation

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