FOXA1 is a potential oncogene in anaplastic thyroid carcinoma

Carmelo Nucera; J Eeckhoute; S Finn; Js Carroll; Ah Ligon; Carmen Priolo; Guido Fadda; M Toner; O Sheils; M Attard; Alfredo Pontecorvi; V Nose; M Loda; M. Brown

doi:10.1158/1078-0432.CCR-08-3155

FOXA1 is a potential oncogene in anaplastic thyroid carcinoma

Carmelo Nucera
, J Eeckhoute
, S Finn
, Js Carroll
, Ah Ligon
, Carmen Priolo
, Guido Fadda
, M Toner
, O Sheils
, M Attard
, Alfredo Pontecorvi
, V Nose
, M Loda
, M. Brown

Research output: Contribution to journal › Article

59 Citations (Scopus)

Abstract

FOXA1 is a mammalian endodermal transcription factor belonging to the human forkhead box gene family that plays a role in certain tumor types. Here, we investigated the potential role of FOXA1 in human thyroid carcinomas.

Original language	English
Pages (from-to)	3680-3689
Number of pages	10
Journal	Clinical Cancer Research
Volume	15
DOIs	https://doi.org/10.1158/1078-0432.CCR-08-3155
Publication status	Published - 2009

Keywords

Adult
Aged
Aged, 80 and over
Apoptosis
Blotting, Western
Carcinoma
Cell Proliferation
Cohort Studies
Cyclin-Dependent Kinase Inhibitor p27
Female
Flow Cytometry
Gene Dosage
Gene Expression Regulation, Neoplastic
Hepatocyte Nuclear Factor 3-alpha
Humans
Immunohistochemistry
In Situ Hybridization, Fluorescence
Intracellular Signaling Peptides and Proteins
Male
Middle Aged
Oncogene Proteins
RNA, Small Interfering
Thyroid Neoplasms
Tissue Array Analysis
Transfection

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10.1158/1078-0432.CCR-08-3155

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title = "FOXA1 is a potential oncogene in anaplastic thyroid carcinoma",

abstract = "FOXA1 is a mammalian endodermal transcription factor belonging to the human forkhead box gene family that plays a role in certain tumor types. Here, we investigated the potential role of FOXA1 in human thyroid carcinomas.",

keywords = "Adult, Aged, Aged, 80 and over, Apoptosis, Blotting, Western, Carcinoma, Cell Proliferation, Cohort Studies, Cyclin-Dependent Kinase Inhibitor p27, Female, Flow Cytometry, Gene Dosage, Gene Expression Regulation, Neoplastic, Hepatocyte Nuclear Factor 3-alpha, Humans, Immunohistochemistry, In Situ Hybridization, Fluorescence, Intracellular Signaling Peptides and Proteins, Male, Middle Aged, Oncogene Proteins, RNA, Small Interfering, Thyroid Neoplasms, Tissue Array Analysis, Transfection, Adult, Aged, Aged, 80 and over, Apoptosis, Blotting, Western, Carcinoma, Cell Proliferation, Cohort Studies, Cyclin-Dependent Kinase Inhibitor p27, Female, Flow Cytometry, Gene Dosage, Gene Expression Regulation, Neoplastic, Hepatocyte Nuclear Factor 3-alpha, Humans, Immunohistochemistry, In Situ Hybridization, Fluorescence, Intracellular Signaling Peptides and Proteins, Male, Middle Aged, Oncogene Proteins, RNA, Small Interfering, Thyroid Neoplasms, Tissue Array Analysis, Transfection",

author = "Carmelo Nucera and J Eeckhoute and S Finn and Js Carroll and Ah Ligon and Carmen Priolo and Guido Fadda and M Toner and O Sheils and M Attard and Alfredo Pontecorvi and V Nose and M Loda and M. Brown",

year = "2009",

doi = "10.1158/1078-0432.CCR-08-3155",

language = "English",

volume = "15",

pages = "3680--3689",

journal = "Clinical Cancer Research",

issn = "1078-0432",

publisher = "American Association for Cancer Research Inc.",

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T1 - FOXA1 is a potential oncogene in anaplastic thyroid carcinoma

AU - Nucera, Carmelo

AU - Eeckhoute, J

AU - Finn, S

AU - Carroll, Js

AU - Ligon, Ah

AU - Priolo, Carmen

AU - Fadda, Guido

AU - Toner, M

AU - Sheils, O

AU - Attard, M

AU - Pontecorvi, Alfredo

AU - Nose, V

AU - Loda, M

AU - Brown, M.

PY - 2009

Y1 - 2009

N2 - FOXA1 is a mammalian endodermal transcription factor belonging to the human forkhead box gene family that plays a role in certain tumor types. Here, we investigated the potential role of FOXA1 in human thyroid carcinomas.

AB - FOXA1 is a mammalian endodermal transcription factor belonging to the human forkhead box gene family that plays a role in certain tumor types. Here, we investigated the potential role of FOXA1 in human thyroid carcinomas.

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - Apoptosis

KW - Blotting, Western

KW - Carcinoma

KW - Cell Proliferation

KW - Cohort Studies

KW - Cyclin-Dependent Kinase Inhibitor p27

KW - Female

KW - Flow Cytometry

KW - Gene Dosage

KW - Gene Expression Regulation, Neoplastic

KW - Hepatocyte Nuclear Factor 3-alpha

KW - Humans

KW - Immunohistochemistry

KW - In Situ Hybridization, Fluorescence

KW - Intracellular Signaling Peptides and Proteins

KW - Male

KW - Middle Aged

KW - Oncogene Proteins

KW - RNA, Small Interfering

KW - Thyroid Neoplasms

KW - Tissue Array Analysis

KW - Transfection

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - Apoptosis

KW - Blotting, Western

KW - Carcinoma

KW - Cell Proliferation

KW - Cohort Studies

KW - Cyclin-Dependent Kinase Inhibitor p27

KW - Female

KW - Flow Cytometry

KW - Gene Dosage

KW - Gene Expression Regulation, Neoplastic

KW - Hepatocyte Nuclear Factor 3-alpha

KW - Humans

KW - Immunohistochemistry

KW - In Situ Hybridization, Fluorescence

KW - Intracellular Signaling Peptides and Proteins

KW - Male

KW - Middle Aged

KW - Oncogene Proteins

KW - RNA, Small Interfering

KW - Thyroid Neoplasms

KW - Tissue Array Analysis

KW - Transfection

UR - http://hdl.handle.net/10807/22549

U2 - 10.1158/1078-0432.CCR-08-3155

DO - 10.1158/1078-0432.CCR-08-3155

M3 - Article

SN - 1078-0432

VL - 15

SP - 3680

EP - 3689

JO - Clinical Cancer Research

JF - Clinical Cancer Research

ER -

FOXA1 is a potential oncogene in anaplastic thyroid carcinoma

Abstract

Keywords

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