Fibrous Dysplasia of the Rib Mimicking a Malignant Bone Tumor at SPECT/CT with 99mTc-MDP

Ludovic Fournel; Cristian Rapicetta; Alessandro Fraternali; Salvatore Bellafiore; Massimiliano Paci; Filippo Lococo

doi:10.1097/RLU.0000000000002015

Fibrous Dysplasia of the Rib Mimicking a Malignant Bone Tumor at SPECT/CT with 99mTc-MDP

Ludovic Fournel
, Cristian Rapicetta
, Alessandro Fraternali
, Salvatore Bellafiore
, Massimiliano Paci
, Filippo Lococo

Université Paris Cité
Azienda Ospedaliera Santa Maria Nuova di Reggio Emilia

Research output: Contribution to journal › Article

3 Citations (Scopus)

Abstract

We herein report a case of a 43-year-old man with a right 8th-rib bone tumor exhibiting features of malignancy at CT-scan. Considering that a SPECT/CT with 99mTc-MDP showed solitary intense radio-tracer uptake and the inconclusive results from a fine-needle biopsy, surgical en bloc tumor resection was performed. Pathologic analysis revealed a well-limited benign bone lesion ("fibrous rib dysplasia") composed by a cellular fibrous proliferation. Since benign osseous diseases may present an intense scintigraphic tracer uptake (as in this case), we suggest a certain caution when interpreting the results of SPECT/CT with 99mTc-MDP in order to avoid misdiagnosis and wrong treatments.

Original language	English
Pages (from-to)	346-348
Number of pages	3
Journal	Clinical Nuclear Medicine
Volume	43
DOIs	https://doi.org/10.1097/RLU.0000000000002015
Publication status	Published - 2018

Keywords

99m
SPECT/CT with
Tc-MDP
osseous fibrous dysplasia
scintigraphy

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10.1097/RLU.0000000000002015

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title = "Fibrous Dysplasia of the Rib Mimicking a Malignant Bone Tumor at SPECT/CT with 99mTc-MDP",

abstract = "We herein report a case of a 43-year-old man with a right 8th-rib bone tumor exhibiting features of malignancy at CT-scan. Considering that a SPECT/CT with 99mTc-MDP showed solitary intense radio-tracer uptake and the inconclusive results from a fine-needle biopsy, surgical en bloc tumor resection was performed. Pathologic analysis revealed a well-limited benign bone lesion ({"}fibrous rib dysplasia{"}) composed by a cellular fibrous proliferation. Since benign osseous diseases may present an intense scintigraphic tracer uptake (as in this case), we suggest a certain caution when interpreting the results of SPECT/CT with 99mTc-MDP in order to avoid misdiagnosis and wrong treatments.",

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author = "Ludovic Fournel and Cristian Rapicetta and Alessandro Fraternali and Salvatore Bellafiore and Massimiliano Paci and Filippo Lococo",

year = "2018",

doi = "10.1097/RLU.0000000000002015",

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pages = "346--348",

journal = "Clinical Nuclear Medicine",

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T1 - Fibrous Dysplasia of the Rib Mimicking a Malignant Bone Tumor at SPECT/CT with 99mTc-MDP

AU - Fournel, Ludovic

AU - Rapicetta, Cristian

AU - Fraternali, Alessandro

AU - Bellafiore, Salvatore

AU - Paci, Massimiliano

AU - Lococo, Filippo

PY - 2018

Y1 - 2018

N2 - We herein report a case of a 43-year-old man with a right 8th-rib bone tumor exhibiting features of malignancy at CT-scan. Considering that a SPECT/CT with 99mTc-MDP showed solitary intense radio-tracer uptake and the inconclusive results from a fine-needle biopsy, surgical en bloc tumor resection was performed. Pathologic analysis revealed a well-limited benign bone lesion ("fibrous rib dysplasia") composed by a cellular fibrous proliferation. Since benign osseous diseases may present an intense scintigraphic tracer uptake (as in this case), we suggest a certain caution when interpreting the results of SPECT/CT with 99mTc-MDP in order to avoid misdiagnosis and wrong treatments.

AB - We herein report a case of a 43-year-old man with a right 8th-rib bone tumor exhibiting features of malignancy at CT-scan. Considering that a SPECT/CT with 99mTc-MDP showed solitary intense radio-tracer uptake and the inconclusive results from a fine-needle biopsy, surgical en bloc tumor resection was performed. Pathologic analysis revealed a well-limited benign bone lesion ("fibrous rib dysplasia") composed by a cellular fibrous proliferation. Since benign osseous diseases may present an intense scintigraphic tracer uptake (as in this case), we suggest a certain caution when interpreting the results of SPECT/CT with 99mTc-MDP in order to avoid misdiagnosis and wrong treatments.

KW - 99m

KW - SPECT/CT with

KW - Tc-MDP

KW - osseous fibrous dysplasia

KW - scintigraphy

KW - 99m

KW - SPECT/CT with

KW - Tc-MDP

KW - osseous fibrous dysplasia

KW - scintigraphy

UR - http://hdl.handle.net/10807/152003

U2 - 10.1097/RLU.0000000000002015

DO - 10.1097/RLU.0000000000002015

M3 - Article

SN - 0363-9762

VL - 43

SP - 346

EP - 348

JO - Clinical Nuclear Medicine

JF - Clinical Nuclear Medicine

ER -

Fibrous Dysplasia of the Rib Mimicking a Malignant Bone Tumor at SPECT/CT with 99mTc-MDP

Abstract

Keywords

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