Fertility preservation in patients with BRCA mutations or Lynch syndrome

Giovanni Scambia, Anna Fagotti, Giacomo Corrado, Rita Trozzi

Research output: Contribution to journalArticle

1 Citation (Scopus)


Guidelines and expert consensus are lacking on fertility preservation in BRCA mutation carriers and in patients with Lynch syndrome. The safety of fertility preservation in this setting is still a topic of debate and multiple factors need to be carefully considered. The aim of this review was to analyze the reproductive potential of women harboring a genetic mutation affecting the DNA repair system and explore the efficacy and safety of existing fertility preservation strategies in these patients.
Original languageEnglish
Pages (from-to)332-338
Number of pages7
JournalInternational Journal of Gynecological Cancer
Publication statusPublished - 2021


  • BRCA1 protein
  • BRCA2 protein
  • lynch syndrome II

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