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Fecal microbiota transplantation in gastrointestinal and extraintestinal disorders

Research output: Contribution to journalArticle

Abstract

Fecal microbiota transplantation (FMT) is the infusion of feces from a healthy donor into the gut of a recipient to treat a dysbiosis-related disease. FMT has been proven to be a safe and effective treatment for Clostridioides difficile infection, but increasing evidence supports the role of FMT in other gastrointestinal and extraintestinal diseases. The aim of this review is to paint the landscape of current evidence of FMT in different fields of application (including irritable bowel syndrome, inflammatory bowel disease, liver disorders, decolonization of multidrug-resistant bacteria, metabolic disorders and neurological disorders), as well as to discuss the current regulatory scenario of FMT, and hypothesize future directions of FMT.
Original languageEnglish
Pages (from-to)1173-1186
Number of pages14
JournalFuture Microbiology
Volume15
Issue number12
DOIs
Publication statusPublished - 2020

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Microbiology (medical)

Keywords

  • Animals
  • Clostridium difficile
  • Fecal Microbiota Transplantation
  • Gastrointestinal Microbiome
  • Humans
  • Intestinal Diseases
  • Metabolic Diseases
  • Nervous System Diseases
  • cancer
  • fecal microbiota transplantation
  • inflammatory bowel disease
  • irritable bowel syndrome
  • metabolic syndrome
  • microbiome
  • microbiota

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