ESTRO ACROP guidelines for the delineation of lymph nodal areas in upper gastrointestinal malignancies

Vincenzo Valentini, Francesco Cellini, Angela Riddell, Thomas B. Brunner, Falk Roeder, Felice Giuliante, Sergio Alfieri, Riccardo Manfredi, Francesco Ardito, Claudio Fiorillo, Venanzio Porziella, Alessio G. Morganti, Alessio Giuseppe Morganti, Karin Haustermans, Stefano Margaritora, Berardino De Bari, Oscar Matzinger, Eleni Gkika, Claus Belka, William AllumMarcel Verheij

Research output: Contribution to journalArticlepeer-review


The European SocieTy for Radiation and Oncology -Advisory Committee on Radiation Oncology Practice (ESTRO-ACROP) endorsed a project to provide guidelines (GL) for the identification and delineation of clinically negative lymph-nodal stations (LNs) involved in upper gastrointestinal clinical scenarios. The presented GL is focused on preoperative (or definitive) setting. The project aim is to improve the consistency of clinical target volume (CTV) delineation by providing: a description of the anatomical boundaries of the LNs; a radiological computed tomography-based atlas depicting the LNs areas; a free, web-based, interactive example case for independent training of radiation oncologists on LNs delineation according to the presented GL, by both qualitative and quantitative analysis (through the FALCON EduCase platform). This project was carried out with the intention to facilitate and improve uniformity of future upper gastrointestinal guidelines on nodal CTV delineation. We report methodology and results from the collaboration of a working group panel selected by the ESTRO-ACROP.
Original languageEnglish
Pages (from-to)92-97
Number of pages6
JournalRadiotherapy and Oncology
Publication statusPublished - 2021


  • Contouring
  • Delineation
  • Gastrointestinal Neoplasms
  • Humans
  • Lymph Nodes
  • Radiation Oncology
  • Radiotherapy
  • Radiotherapy Planning, Computer-Assisted
  • Target
  • Target volumes
  • Tomography, X-Ray Computed
  • Upper gastrointestinal malignancies, lymph-nodes


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