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Estimating β-casomorphin-7 exposure from milk and dairy product consumption: a comprehensive assessment for the European population

  • University of Bologna

Research output: Contribution to journalArticle

Abstract

β-Casomorphin-7 (BCM-7), a heptapeptide derived from β-casein hydrolysis, has gained attention for its potential role in gastrointestinal discomfort and certain diseases, yet its effects remain controversial. This study aimed to provide the first reliable estimation of BCM-7 exposure for low, medium and high consumers of milk and dairy products in the European population. We developed a database on BCM-7 released after simulated digestion, combining literature review and direct analysis of milk and selected dairy products. Using European food consumption data, we estimated BCM-7 daily exposure for adults (132–2541 μg), adolescents (163–2594 μg) and children (200–2357 μg). Milk emerged as the most significant source of BCM-7 exposure across all population groups. Statistical analysis revealed differences in exposure levels between adults and children at medium consumption levels. This work provides the first comprehensive estimation of dietary BCM-7 exposure, laying the groundwork for future research on its potential health effects.
Original languageEnglish
Pages (from-to)571-580
Number of pages10
JournalInternational Journal of Food Sciences and Nutrition
Volume76
Issue number5
DOIs
Publication statusPublished - 2025

All Science Journal Classification (ASJC) codes

  • Food Science

Keywords

  • BCM-7
  • bioactive peptides
  • dairy consumption
  • exposure
  • in vitro digestion
  • β-Casomorphin-7

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