ESGAR consensus statement on liver MR imaging and clinical use of liver-specific contrast agents

Riccardo Manfredi, E. Neri, M. A. Bali, A. Ba-Ssalamah, P. Boraschi, G. Brancatelli, F. Caseiro Alves, L. Grazioli, T. Helmberger, J. M. Lee, L. Martì-Bonmatì, C. Matos, E. M. Merkle, B. Op De Beeck, W. Schima, S. Skehan, V. Vilgrain, C. Zech, C. Bartolozzi

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85 Citations (Scopus)

Abstract

Objectives: To develop a consensus and provide updated recommendations on liver MR imaging and the clinical use of liver-specific contrast agents. Methods: The European Society of Gastrointestinal and Abdominal Radiology (ESGAR) formed a multinational European panel of experts, selected on the basis of a literature review and their leadership in the field of liver MR imaging. A modified Delphi process was adopted to draft a list of statements. Descriptive and Cronbach’s statistics were used to rate levels of agreement and internal reliability of the consensus. Results: Three Delphi rounds were conducted and 76 statements composed on MR technique (n = 17), clinical application of liver-specific contrast agents in benign, focal liver lesions (n = 7), malignant liver lesions in non-cirrhotic (n = 9) and in cirrhotic patients (n = 18), diffuse and vascular liver diseases (n = 12), and bile ducts (n = 13). The overall mean score of agreement was 4.84 (SD ±0.17). Full consensus was reached in 22 % of all statements in all working groups, with no full consensus reached on diffuse and vascular diseases. Conclusions: The consensus provided updated recommendations on the methodology, and clinical indications, of MRI with liver specific contrast agents in the study of liver diseases. Key points: • Liver-specific contrast agents are recommended in MRI of the liver. • The hepatobiliary phase improves the detection and characterization of hepatocellular lesions. • Liver-specific contrast agents can improve the detection of HCC.
Original languageEnglish
Pages (from-to)921-931
Number of pages11
JournalEuropean Radiology
Volume26
DOIs
Publication statusPublished - 2016

Keywords

  • Adenoma, Liver Cell
  • Bile Ducts
  • Biliary tract
  • Consensus
  • Contrast Media
  • Contrast media
  • Delphi Technique
  • Delphi technique
  • Diagnosis, Differential
  • Humans
  • Liver
  • Liver Diseases
  • Liver Neoplasms
  • Magnetic Resonance Imaging
  • Magnetic resonance imaging
  • Radiography, Abdominal
  • Reproducibility of Results

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