Elevated 1-hour postload plasma glucose levels identify subjects with normal glucose tolerance but impaired β-cell function, insulin resistance, and worse cardiovascular risk profile: the GENFIEV study

Andrea Giaccari, Cristina Bianchi, Roberto Miccoli, Maddalena Trombetta, Francesco Giorgino, Simona Frontoni, Emanuela Faloia, Giulio Marchesini, Maria A. Dolci, Franco Cavalot, Gisella Cavallo, Frida Leonetti, Riccardo C. Bonadonna, Stefano Del Prato

Research output: Contribution to journalArticlepeer-review

77 Citations (Scopus)

Abstract

In subjects with normal glucose tolerance (NGT) 1-hour postload plasma glucose (1-h oral glucose tolerance test [OGTT]) of >155 mg/dL predicts type 2 diabetes (T2DM) and is associated with subclinical atherosclerosis.
Original languageEnglish
Pages (from-to)2100-2105
Number of pages6
JournalTHE JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM
Volume98
DOIs
Publication statusPublished - 2013

Keywords

  • Adult
  • Blood Glucose
  • Body Mass Index
  • Cardiovascular Diseases
  • Cross-Sectional Studies
  • Diabetes Mellitus, Type 2
  • Glucose Intolerance
  • Glucose Tolerance Test
  • Humans
  • Insulin
  • Insulin Resistance
  • Insulin-Secreting Cells
  • Overweight
  • Prediabetic State

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