Electrochemical Liposome-Based Biosensors for Nucleic Acid Detection

Diego Voccia, Francesca Bettazzi, Ilaria Palchetti

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

MicroRNAs (miRNAs) are intensely studied as candidates for diagnostic and prognostic clinical biomarkers. Faradic impedance spectroscopy (EIS) and differential pulse voltammetry (DPV), coupled to disposable gold electrodes and enzyme amplification of the hybridization event, were used for the development of biosensors for the detection of miRNAs. Biotin-labeled liposomes were employed as nanointerfaces that amplify the primary miRNA-sensing events by their association to the probe–/DNA–miRNA–analyte complex generated onto the transducer.
Original languageEnglish
Title of host publicationSensors and Microsystems
Pages179-182
Number of pages4
Volume268
DOIs
Publication statusPublished - 2014
Event17th National Conference, Brescia, Italy, 5-7 February 2013 - BRESCIA -- ITA
Duration: 5 Feb 20137 Feb 2013

Publication series

NameLECTURE NOTES IN ELECTRICAL ENGINEERING

Conference

Conference17th National Conference, Brescia, Italy, 5-7 February 2013
CityBRESCIA -- ITA
Period5/2/137/2/13

Keywords

  • Chronic Lymphocytic Leukemia Differential Pulse Voltammetry Electrochemical Signal Electron Transfer Resistance miRNA Detection

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