Effects of drospirenone-ethinylestradiol and/or metformin on CD4(+)CD28(null) T lymphocytes frequency in women with hyperinsulinemia having polycystic ovary syndrome: a randomized clinical trial

Giovanna Liuzzo, Antonio Lanzone, Rosanna Apa, Francesca Moro, Andrea Morciano, Anna Tropea, Francesca Sagnella, Elisa Scarinci, Andrea Ciardulli, Daniela Martinez, Alessandra Familiari, Giampaolo Niccoli

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

To evaluate the long-term effects of drospirenone (DRSP)/ethinylestradiol (EE) alone, metformin alone, and DRSP/EE-metformin on CD4(+)CD28(null) T lymphocytes frequency, a cardiovascular risk marker, in patients with hyperinsulinemic polycystic ovary syndrome (PCOS).
Original languageEnglish
Pages (from-to)1508-1517
Number of pages10
JournalReproductive Sciences
Volume20
DOIs
Publication statusPublished - 2013

Keywords

  • CD4+CD28null T-lymphocytes
  • drospirenone
  • ethinylestradiol
  • metformin
  • polycystic ovary syndrome

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