Effects of drospirenone-ethinylestradiol and/or metformin on CD4(+)CD28(null) T lymphocytes frequency in women with hyperinsulinemia having polycystic ovary syndrome: a randomized clinical trial

F Moro; A Morciano; Anna Tropea; F Sagnella; C Palla; E Scarinci; A Ciardulli; D Martinez; Alessandra Familiari; Giovanna Liuzzo; A Tritarelli; N Cosentino; G Niccoli; F Crea; Antonio Lanzone; Rosanna Apa

doi:10.1177/1933719113488444

Effects of drospirenone-ethinylestradiol and/or metformin on CD4(+)CD28(null) T lymphocytes frequency in women with hyperinsulinemia having polycystic ovary syndrome: a randomized clinical trial

F Moro
, A Morciano^*
, Anna Tropea
, F Sagnella
, C Palla
, E Scarinci
, A Ciardulli
, D Martinez
, Alessandra Familiari
, Giovanna Liuzzo
, A Tritarelli
, N Cosentino
, G Niccoli
, F Crea
, Antonio Lanzone
, Rosanna Apa

^*Corresponding author

IRCCS Oasi Maria SS. - Troina (EN)

Research output: Contribution to journal › Article

14 Citations (Scopus)

Abstract

To evaluate the long-term effects of drospirenone (DRSP)/ethinylestradiol (EE) alone, metformin alone, and DRSP/EE-metformin on CD4(+)CD28(null) T lymphocytes frequency, a cardiovascular risk marker, in patients with hyperinsulinemic polycystic ovary syndrome (PCOS).

Original language	English
Pages (from-to)	1508-1517
Number of pages	10
Journal	Reproductive Sciences
Volume	20
Issue number	12
DOIs	https://doi.org/10.1177/1933719113488444
Publication status	Published - 2013

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

Obstetrics and Gynaecology

Keywords

Adolescent
Adult
Analysis of Variance
Androstenes
Antigens
CD28
CD4 Lymphocyte Count
CD4+CD28null T-lymphocytes
CD4-Positive T-Lymphocytes
Cardiovascular Diseases
Chi-Square Distribution
Ethinyl Estradiol
Female
Humans
Hyperinsulinism
Hypoglycemic Agents
Metformin
Polycystic Ovary Syndrome
Reproductive Control Agents
Risk Factors
Rome
Time Factors
Treatment Outcome
Young Adult
drospirenone
ethinylestradiol
metformin
polycystic ovary syndrome

Access to Document

10.1177/1933719113488444

Cite this

Moro, F., Morciano, A., Tropea, A., Sagnella, F., Palla, C., Scarinci, E., Ciardulli, A., Martinez, D., Familiari, A., Liuzzo, G., Tritarelli, A., Cosentino, N., Niccoli, G., Crea, F., Lanzone, A., & Apa, R. (2013). Effects of drospirenone-ethinylestradiol and/or metformin on CD4(+)CD28(null) T lymphocytes frequency in women with hyperinsulinemia having polycystic ovary syndrome: a randomized clinical trial. Reproductive Sciences, 20(12), 1508-1517. https://doi.org/10.1177/1933719113488444

@article{f68776c1e325472ebd309dfeab2394c2,

title = "Effects of drospirenone-ethinylestradiol and/or metformin on CD4(+)CD28(null) T lymphocytes frequency in women with hyperinsulinemia having polycystic ovary syndrome: a randomized clinical trial",

abstract = "To evaluate the long-term effects of drospirenone (DRSP)/ethinylestradiol (EE) alone, metformin alone, and DRSP/EE-metformin on CD4(+)CD28(null) T lymphocytes frequency, a cardiovascular risk marker, in patients with hyperinsulinemic polycystic ovary syndrome (PCOS).",

keywords = "Adolescent, Adult, Analysis of Variance, Androstenes, Antigens, CD28, CD4 Lymphocyte Count, CD4+CD28null T-lymphocytes, CD4-Positive T-Lymphocytes, Cardiovascular Diseases, Chi-Square Distribution, Ethinyl Estradiol, Female, Humans, Hyperinsulinism, Hypoglycemic Agents, Metformin, Polycystic Ovary Syndrome, Reproductive Control Agents, Risk Factors, Rome, Time Factors, Treatment Outcome, Young Adult, drospirenone, ethinylestradiol, metformin, polycystic ovary syndrome, Adolescent, Adult, Analysis of Variance, Androstenes, Antigens, CD28, CD4 Lymphocyte Count, CD4+CD28null T-lymphocytes, CD4-Positive T-Lymphocytes, Cardiovascular Diseases, Chi-Square Distribution, Ethinyl Estradiol, Female, Humans, Hyperinsulinism, Hypoglycemic Agents, Metformin, Polycystic Ovary Syndrome, Reproductive Control Agents, Risk Factors, Rome, Time Factors, Treatment Outcome, Young Adult, drospirenone, ethinylestradiol, metformin, polycystic ovary syndrome",

author = "F Moro and A Morciano and Anna Tropea and F Sagnella and C Palla and E Scarinci and A Ciardulli and D Martinez and Alessandra Familiari and Giovanna Liuzzo and A Tritarelli and N Cosentino and G Niccoli and F Crea and Antonio Lanzone and Rosanna Apa",

year = "2013",

doi = "10.1177/1933719113488444",

language = "English",

volume = "20",

pages = "1508--1517",

journal = "Reproductive Sciences",

issn = "1933-7191",

publisher = "Springer Nature",

number = "12",

}

Moro, F, Morciano, A, Tropea, A, Sagnella, F, Palla, C, Scarinci, E, Ciardulli, A, Martinez, D, Familiari, A , Liuzzo, G, Tritarelli, A, Cosentino, N, Niccoli, G, Crea, F, Lanzone, A & Apa, R 2013, 'Effects of drospirenone-ethinylestradiol and/or metformin on CD4(+)CD28(null) T lymphocytes frequency in women with hyperinsulinemia having polycystic ovary syndrome: a randomized clinical trial', Reproductive Sciences, vol. 20, no. 12, pp. 1508-1517. https://doi.org/10.1177/1933719113488444

TY - JOUR

T1 - Effects of drospirenone-ethinylestradiol and/or metformin on CD4(+)CD28(null) T lymphocytes frequency in women with hyperinsulinemia having polycystic ovary syndrome: a randomized clinical trial

AU - Moro, F

AU - Morciano, A

AU - Tropea, Anna

AU - Sagnella, F

AU - Palla, C

AU - Scarinci, E

AU - Ciardulli, A

AU - Martinez, D

AU - Familiari, Alessandra

AU - Liuzzo, Giovanna

AU - Tritarelli, A

AU - Cosentino, N

AU - Niccoli, G

AU - Crea, F

AU - Lanzone, Antonio

AU - Apa, Rosanna

PY - 2013

Y1 - 2013

N2 - To evaluate the long-term effects of drospirenone (DRSP)/ethinylestradiol (EE) alone, metformin alone, and DRSP/EE-metformin on CD4(+)CD28(null) T lymphocytes frequency, a cardiovascular risk marker, in patients with hyperinsulinemic polycystic ovary syndrome (PCOS).

AB - To evaluate the long-term effects of drospirenone (DRSP)/ethinylestradiol (EE) alone, metformin alone, and DRSP/EE-metformin on CD4(+)CD28(null) T lymphocytes frequency, a cardiovascular risk marker, in patients with hyperinsulinemic polycystic ovary syndrome (PCOS).

KW - Adolescent

KW - Adult

KW - Analysis of Variance

KW - Androstenes

KW - Antigens

KW - CD28

KW - CD4 Lymphocyte Count

KW - CD4+CD28null T-lymphocytes

KW - CD4-Positive T-Lymphocytes

KW - Cardiovascular Diseases

KW - Chi-Square Distribution

KW - Ethinyl Estradiol

KW - Female

KW - Humans

KW - Hyperinsulinism

KW - Hypoglycemic Agents

KW - Metformin

KW - Polycystic Ovary Syndrome

KW - Reproductive Control Agents

KW - Risk Factors

KW - Rome

KW - Time Factors

KW - Treatment Outcome

KW - Young Adult

KW - drospirenone

KW - ethinylestradiol

KW - metformin

KW - polycystic ovary syndrome

KW - Adolescent

KW - Adult

KW - Analysis of Variance

KW - Androstenes

KW - Antigens

KW - CD28

KW - CD4 Lymphocyte Count

KW - CD4+CD28null T-lymphocytes

KW - CD4-Positive T-Lymphocytes

KW - Cardiovascular Diseases

KW - Chi-Square Distribution

KW - Ethinyl Estradiol

KW - Female

KW - Humans

KW - Hyperinsulinism

KW - Hypoglycemic Agents

KW - Metformin

KW - Polycystic Ovary Syndrome

KW - Reproductive Control Agents

KW - Risk Factors

KW - Rome

KW - Time Factors

KW - Treatment Outcome

KW - Young Adult

KW - drospirenone

KW - ethinylestradiol

KW - metformin

KW - polycystic ovary syndrome

UR - https://publicatt.unicatt.it/handle/10807/62061

UR - https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=84887453332&origin=inward

UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84887453332&origin=inward

U2 - 10.1177/1933719113488444

DO - 10.1177/1933719113488444

M3 - Article

SN - 1933-7191

VL - 20

SP - 1508

EP - 1517

JO - Reproductive Sciences

JF - Reproductive Sciences

IS - 12

ER -

Effects of drospirenone-ethinylestradiol and/or metformin on CD4(+)CD28(null) T lymphocytes frequency in women with hyperinsulinemia having polycystic ovary syndrome: a randomized clinical trial

Abstract

UN SDGs

All Science Journal Classification (ASJC) codes

Keywords

Access to Document

Other files and links

Fingerprint

Cite this