Ecofriendly synergists for insecticide formulations (EcoSyn)

Valerio Borzatta; Francesco Tozzi; Mark Johnston; Alan Dewar; Chris Bass; Lin Field; Dalibor Titera; Mark Kamler; Michela Panini; Emanuele Mazzoni; Graham Moores

Ecofriendly synergists for insecticide formulations (EcoSyn)

Valerio Borzatta, Francesco Tozzi, Mark Johnston, Alan Dewar, Chris Bass, Lin Field, Dalibor Titera, Mark Kamler, Michela Panini, Emanuele Mazzoni, Graham Moores

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

EcoSyn consists of a consortium of experts to optimise the use of synergists in agriculture and public health by elucidating the relationship between synergist chemical structure and activity on a variety of target insect metabolic enzymes: this will enhance the efficacy of insecticides against resistant and susceptible pest insects in both laboratory and field environments. Repeated use of synthetic insecticides has resulted in the development of insecticide resistance; inhibition of insect defence enzymes by synergists would allow increased kill of resistant pests and control of susceptible pests with reduced insecticidal rates. EcoSyn has characterised interactions of novel synergists based on PBO (piperonyl butoxide) against known resistance-conferring P450/esterase proteins by both in vitro and in vivo assays. Candidate synergists have also been tested against pollinators and in long-term selection experiments to investigate changes in insect pest transcriptome

Original language	English
Title of host publication	Resistance 2015 - Abstract Book
Pages	86
Number of pages	1
Publication status	Published - 2015
Event	Resistance 2015 - Rothamsted Research, Harpenden (UK) Duration: 14 Sept 2015 → 16 Sept 2015

Conference

Conference	Resistance 2015
City	Rothamsted Research, Harpenden (UK)
Period	14/9/15 → 16/9/15

Keywords

PBO
synergists

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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title = "Ecofriendly synergists for insecticide formulations (EcoSyn)",

abstract = "EcoSyn consists of a consortium of experts to optimise the use of synergists in agriculture and public health by elucidating the relationship between synergist chemical structure and activity on a variety of target insect metabolic enzymes: this will enhance the efficacy of insecticides against resistant and susceptible pest insects in both laboratory and field environments. Repeated use of synthetic insecticides has resulted in the development of insecticide resistance; inhibition of insect defence enzymes by synergists would allow increased kill of resistant pests and control of susceptible pests with reduced insecticidal rates. EcoSyn has characterised interactions of novel synergists based on PBO (piperonyl butoxide) against known resistance-conferring P450/esterase proteins by both in vitro and in vivo assays. Candidate synergists have also been tested against pollinators and in long-term selection experiments to investigate changes in insect pest transcriptome",

keywords = "PBO, synergists, PBO, synergists",

author = "Valerio Borzatta and Francesco Tozzi and Mark Johnston and Alan Dewar and Chris Bass and Lin Field and Dalibor Titera and Mark Kamler and Michela Panini and Emanuele Mazzoni and Graham Moores",

year = "2015",

language = "English",

pages = "86",

booktitle = "Resistance 2015 - Abstract Book",

note = "Resistance 2015 ; Conference date: 14-09-2015 Through 16-09-2015",

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TY - GEN

T1 - Ecofriendly synergists for insecticide formulations (EcoSyn)

AU - Borzatta, Valerio

AU - Tozzi, Francesco

AU - Johnston, Mark

AU - Dewar, Alan

AU - Bass, Chris

AU - Field, Lin

AU - Titera, Dalibor

AU - Kamler, Mark

AU - Panini, Michela

AU - Mazzoni, Emanuele

AU - Moores, Graham

PY - 2015

Y1 - 2015

N2 - EcoSyn consists of a consortium of experts to optimise the use of synergists in agriculture and public health by elucidating the relationship between synergist chemical structure and activity on a variety of target insect metabolic enzymes: this will enhance the efficacy of insecticides against resistant and susceptible pest insects in both laboratory and field environments. Repeated use of synthetic insecticides has resulted in the development of insecticide resistance; inhibition of insect defence enzymes by synergists would allow increased kill of resistant pests and control of susceptible pests with reduced insecticidal rates. EcoSyn has characterised interactions of novel synergists based on PBO (piperonyl butoxide) against known resistance-conferring P450/esterase proteins by both in vitro and in vivo assays. Candidate synergists have also been tested against pollinators and in long-term selection experiments to investigate changes in insect pest transcriptome

AB - EcoSyn consists of a consortium of experts to optimise the use of synergists in agriculture and public health by elucidating the relationship between synergist chemical structure and activity on a variety of target insect metabolic enzymes: this will enhance the efficacy of insecticides against resistant and susceptible pest insects in both laboratory and field environments. Repeated use of synthetic insecticides has resulted in the development of insecticide resistance; inhibition of insect defence enzymes by synergists would allow increased kill of resistant pests and control of susceptible pests with reduced insecticidal rates. EcoSyn has characterised interactions of novel synergists based on PBO (piperonyl butoxide) against known resistance-conferring P450/esterase proteins by both in vitro and in vivo assays. Candidate synergists have also been tested against pollinators and in long-term selection experiments to investigate changes in insect pest transcriptome

KW - PBO

KW - synergists

KW - PBO

KW - synergists

UR - http://hdl.handle.net/10807/67851

M3 - Conference contribution

SP - 86

BT - Resistance 2015 - Abstract Book

T2 - Resistance 2015

Y2 - 14 September 2015 through 16 September 2015

ER -

Ecofriendly synergists for insecticide formulations (EcoSyn)

Abstract

Conference

Keywords

UN SDGs

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