Early introduction of anakinra improves acute pericarditis and prevents tamponade in Staphylococcal sepsis

Ludovico Luca Sicignano, Maria Grazia Massaro, Marinica Savino, Donato Rigante, Laura Gerardino, Raffaele Manna

Research output: Contribution to journalArticle

Abstract

The clinical response to anakinra observed by this patient concurrently treated with antibiotics indirectly confirms the potentially pathogenic role of IL-1 in maintaining the pericardial disease and shows how IL-1 blockade might allow avoiding the pericardiocentesis procedure. The report supports the hypothesis that anakinra is an effective and safe tool in the early treatment of acute pericarditis of presumed bacterial origin nonresponding to targeted antibiotic therapy.
Original languageEnglish
Pages (from-to)1391-1394
Number of pages4
JournalInternal and Emergency Medicine
Volume2021
DOIs
Publication statusPublished - 2021

Keywords

  • Anakinra
  • Pericarditis

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