Early clinical outcome after aortic root replacement using a biological composite valved graft with and without neo-sinuses

Mario Fulvio Luigi Gaudino, Andrea Salica, Luca Weltert, Monica Munjal, Christopher Lau, Mohamed Elsayed, Ivancarmine Gambardella, Erin Mills, Ruggero De Paulis, Leonard N. Girardi

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

OBJECTIVES: This study was conceived to compare the results of aortic root replacement using a composite biological valved graft with or without neo-sinuses of Valsalva. METHODS: We compared the early clinical outcomes of 421 patients who underwent aortic root replacement using a handmade biological composite valved graft with or without neo-sinuses (198 and 223 patients, respectively). Propensity matching based on the most important preoperative clinical variables resulted in a cohort of 210 patients (105 pairs) with comparable baseline variables. RESULTS: No difference in early clinical outcome was found between the unmatched groups. At a mean follow-up of 28.8 months, 11 patients required reoperation on the aortic valve (2.6%). Seven of the cases of reoperation were in the group without neo-sinuses (P = 0.83). In the propensity-matched groups, the type of graft used did not affect early and late clinical outcome and incidence of reoperations. CONCLUSIONS: The early clinical outcome of patients submitted to aortic root replacement using a handmade biological composite valved graft is equally good in the presence and in the absence of neo-sinuses
Original languageEnglish
Pages (from-to)N/A-N/A
JournalEuropean Journal of Cardio-thoracic Surgery
DOIs
Publication statusPublished - 2016

Keywords

  • Aortic root replacement
  • Biological prosthesis
  • Valsalva sinuses

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