Dose-response effect of baclofen in reducing daily alcohol intake in alcohol dependence: secondary analysis of a randomized, double-blind, placebo-controlled trial

Giovanni Addolorato; L Leggio; A Ferrulli; S Cardone; G Bedogni; F Caputo; Giovanni Battista Gasbarrini; Raffaele Landolfi

doi:10.1093/alcalc/agr017

Dose-response effect of baclofen in reducing daily alcohol intake in alcohol dependence: secondary analysis of a randomized, double-blind, placebo-controlled trial

Giovanni Addolorato
, L Leggio
, A Ferrulli
, S Cardone
, G Bedogni
, F Caputo
, Giovanni Battista Gasbarrini
, Raffaele Landolfi

Research output: Contribution to journal › Article

Abstract

To explore the effect of baclofen in a dose of 20 mg three times per day, compared with the already studied dose of 10 mg three times per day, in the treatment of alcohol dependence.

Original language	English
Pages (from-to)	312-317
Number of pages	6
Journal	Alcohol and Alcoholism
Volume	46
Issue number	3
DOIs	https://doi.org/10.1093/alcalc/agr017
Publication status	Published - 2011

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Adult
Alcohol Drinking
Alcoholism
Baclofen
Central Nervous System Depressants
Dose-Response Relationship
Double-Blind Method
Drug
Ethanol
Female
GABA-B Receptor Agonists
Humans
Male
Middle Aged
Placebos
Treatment Outcome
Young Adult

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10.1093/alcalc/agr017

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title = "Dose-response effect of baclofen in reducing daily alcohol intake in alcohol dependence: secondary analysis of a randomized, double-blind, placebo-controlled trial",

abstract = "To explore the effect of baclofen in a dose of 20 mg three times per day, compared with the already studied dose of 10 mg three times per day, in the treatment of alcohol dependence.",

keywords = "Adult, Alcohol Drinking, Alcoholism, Baclofen, Central Nervous System Depressants, Dose-Response Relationship, Double-Blind Method, Drug, Ethanol, Female, GABA-B Receptor Agonists, Humans, Male, Middle Aged, Placebos, Treatment Outcome, Young Adult, Adult, Alcohol Drinking, Alcoholism, Baclofen, Central Nervous System Depressants, Dose-Response Relationship, Double-Blind Method, Drug, Ethanol, Female, GABA-B Receptor Agonists, Humans, Male, Middle Aged, Placebos, Treatment Outcome, Young Adult",

author = "Giovanni Addolorato and L Leggio and A Ferrulli and S Cardone and G Bedogni and F Caputo and Gasbarrini, \{Giovanni Battista\} and Raffaele Landolfi",

year = "2011",

doi = "10.1093/alcalc/agr017",

language = "English",

volume = "46",

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publisher = "Oxford University Press",

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T1 - Dose-response effect of baclofen in reducing daily alcohol intake in alcohol dependence: secondary analysis of a randomized, double-blind, placebo-controlled trial

AU - Addolorato, Giovanni

AU - Leggio, L

AU - Ferrulli, A

AU - Cardone, S

AU - Bedogni, G

AU - Caputo, F

AU - Gasbarrini, Giovanni Battista

AU - Landolfi, Raffaele

PY - 2011

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N2 - To explore the effect of baclofen in a dose of 20 mg three times per day, compared with the already studied dose of 10 mg three times per day, in the treatment of alcohol dependence.

AB - To explore the effect of baclofen in a dose of 20 mg three times per day, compared with the already studied dose of 10 mg three times per day, in the treatment of alcohol dependence.

KW - Adult

KW - Alcohol Drinking

KW - Alcoholism

KW - Baclofen

KW - Central Nervous System Depressants

KW - Dose-Response Relationship

KW - Double-Blind Method

KW - Drug

KW - Ethanol

KW - Female

KW - GABA-B Receptor Agonists

KW - Humans

KW - Male

KW - Middle Aged

KW - Placebos

KW - Treatment Outcome

KW - Young Adult

KW - Adult

KW - Alcohol Drinking

KW - Alcoholism

KW - Baclofen

KW - Central Nervous System Depressants

KW - Dose-Response Relationship

KW - Double-Blind Method

KW - Drug

KW - Ethanol

KW - Female

KW - GABA-B Receptor Agonists

KW - Humans

KW - Male

KW - Middle Aged

KW - Placebos

KW - Treatment Outcome

KW - Young Adult

UR - https://publicatt.unicatt.it/handle/10807/14195

U2 - 10.1093/alcalc/agr017

DO - 10.1093/alcalc/agr017

M3 - Article

SN - 1464-3502

VL - 46

SP - 312

EP - 317

JO - Alcohol and Alcoholism

JF - Alcohol and Alcoholism

IS - 3

ER -

Dose-response effect of baclofen in reducing daily alcohol intake in alcohol dependence: secondary analysis of a randomized, double-blind, placebo-controlled trial

Abstract

UN SDGs

Keywords

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