Dose-response effect of baclofen in reducing daily alcohol intake in alcohol dependence: secondary analysis of a randomized, double-blind, placebo-controlled trial

Giovanni Addolorato, Giovanni Battista Gasbarrini, Raffaele Landolfi, L Leggio, A Ferrulli, S Cardone, G Bedogni, F Caputo

Research output: Contribution to journalArticle

Abstract

To explore the effect of baclofen in a dose of 20 mg three times per day, compared with the already studied dose of 10 mg three times per day, in the treatment of alcohol dependence.
Original languageEnglish
Pages (from-to)312-317
Number of pages6
JournalAlcohol and Alcoholism
Volume46
DOIs
Publication statusPublished - 2011

Keywords

  • Adult
  • Alcohol Drinking
  • Alcoholism
  • Baclofen
  • Central Nervous System Depressants
  • Dose-Response Relationship, Drug
  • Double-Blind Method
  • Ethanol
  • Female
  • GABA-B Receptor Agonists
  • Humans
  • Male
  • Middle Aged
  • Placebos
  • Treatment Outcome
  • Young Adult

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