Does CD10 expression individuate a GIST subgroup of patients?

Luigi Sofo, Riccardo Ricci, Fausto Rosa, Paola Caprino, Marco Pericoli Ridolfini, Arnaldo Carbone, Antonia Meloscia, Giovanni Doglietto

Research output: Contribution to journalArticlepeer-review


The aim of the study was to evaluate expression of CD10 in a series of gastrointestinal tumors (GIST) and to find its relationship with prognosis, biological and clinical behavior. GISTs represent the most frequent gastrointestinal (GI) mesenchymal tumors. Biological behavior of GIST cannot be easily predicted; for this reason many biomolecular factors are being investigated to predict prognosis. Recently the role of the CD10 as prognostic predictor in the carcinogenesis of the gastrointestinal carcinomas has been accurately studied. To our knowledge, no data regarding the role of CD10 in GISTs have been published to date.
Original languageEnglish
Pages (from-to)271-276
Number of pages6
JournalMinerva Chirurgica
Publication statusPublished - 2014


  • gastrointestinal
  • gist


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