DNA ploidy pattern in human chronic liver diseases and hepatic nodular lesions. Flow cytometric analysis on echo-guided needle liver biopsy

Marcello Anti, G Marra, Gian Ludovico Rapaccini, Carlo Rumi, S Bussa, Guido Fadda, Fabio Maria Vecchio, A Valenti, A Percesepe, Maurizio Pompili

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Significantly elevated fractions of diploid hepatocytes and reduction in the polyploid populations have been reported in human and experimentally induced hepatocellular carcinomas (HCC). This study was conducted to determine how these changes are related to conditions that often precede HCC, such as chronic hepatitis, cirrhosis, and premalignant focal nodules in cirrhotic livers.
Original languageEnglish
Pages (from-to)281-288
Number of pages8
JournalCancer
Volume73
Publication statusPublished - 1994

Keywords

  • Aged
  • Biopsy, Needle
  • Carcinoma, Hepatocellular
  • Chronic Disease
  • DNA
  • Female
  • Flow Cytometry
  • Hepatitis
  • Humans
  • Liver
  • Liver Cirrhosis
  • Liver Diseases
  • Liver Neoplasms
  • Male
  • Middle Aged
  • Ploidies
  • S Phase
  • Ultrasonics

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