Direct evidence for a parietal-frontal pathway subserving spatial awareness in humans

Michel Thiebaut De Schotten, Marika Urbanski, Paolo Bartolomeo, H Duffau, E Volle, R Lévy, B Dubois

Research output: Contribution to journalArticle

472 Citations (Scopus)

Abstract

Intraoperative electrical stimulation, which temporarily inactivates restricted regions during brain surgery, can map cognitive functions in humans with spatiotemporal resolution unmatched by other methods. Using this technique, we found that stimulation of the right inferior parietal lobule or the caudal superior temporal gyrus, but not of its rostral portion, determined rightward deviations on line bisection. However, the strongest shifts occurred with subcortical stimulation. Fiber tracking identified the stimulated site as a section of the superior occipitofrontal fasciculus, a poorly known parietal-frontal pathway. These findings suggest that parietal-frontal communication is necessary for the symmetrical processing of the visual scene.
Original languageEnglish
Pages (from-to)2226-2228
Number of pages3
JournalSCIENCE
Volume309
DOIs
Publication statusPublished - 2005

Keywords

  • Adult
  • Awareness
  • Brain Mapping
  • Brain Neoplasms
  • Electric Stimulation
  • Female
  • Frontal Lobe
  • Glioma
  • Humans
  • Male
  • Nerve Net
  • Neural Pathways
  • Parietal Lobe
  • Perceptual Disorders
  • Space Perception
  • Temporal Lobe

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