Diffuse cutaneous candidiasis in a dog. Diagnosis by PCR-REA

Brunella Posteraro, Annabella Moretti, Luisa Boncio, Luca Mechelli, Emanuele De Gasperis, Francesco Agnetti, Marcello Raspa

Research output: Contribution to journalArticlepeer-review

23 Citations (Scopus)

Abstract

The authors describe a clinical case of cutaneous candidiasis in a dog with dermatological lesions, characterized by persistent alopecia, crusts, ulcers and scales. Predisposing factors such as the use of corticosteroids, the concomitan presence of an autoimmune disease (pemphigus foliaceus) and an infection of ehrlichiosis caused by Ehrlichia canis were observed. Histopathological findings included signs of orthokeratotic hyperkeratosis, moderate follicular keratosis and light epidermic acanthosis. The reactive process included an infiltrative superficial dermatitis and a mural folliculitis with prevalent participation of macrophages and lymphocytes. The application of PCR-Restriction Enzyme Analysis (REA) method on cutaneous specimens in veterinary medicine is an extremely interesting diagnostic tool. Its use, together with other techniques, such as mycologic, cytologic and histological examinations, allowed us to identify Candida albicans as aetiological agent in this particular case.
Original languageEnglish
Pages (from-to)139-142
Number of pages4
JournalRevista Iberoamericana de Micologia
Volume21
Publication statusPublished - 2004

Keywords

  • Adrenal Cortex Hormones
  • Animals
  • Autoimmune Diseases
  • Candida albicans
  • Candidiasis, Cutaneous
  • DNA, Fungal
  • Disease Susceptibility
  • Dog Diseases
  • Dogs
  • Ehrlichia canis
  • Ehrlichiosis
  • Fatal Outcome
  • Immunocompromised Host
  • Male
  • Pemphigus
  • Polymerase Chain Reaction
  • Restriction Mapping

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