Dietary oxalate intake and kidney outcomes

Pietro Manuel Ferraro, Maria Clarissa Tio, Sushrut S. Waikar

Research output: Contribution to journalArticle

4 Citations (Scopus)


Oxalate is both a plant-derived molecule and a terminal toxic metabolite with no known physiological function in humans. It is predominantly eliminated by the kidneys through glomerular filtration and tubular secretion. Regardless of the cause, the increased load of dietary oxalate presented to the kidneys has been linked to different kidney-related conditions and injuries, including calcium oxalate nephrolithiasis, acute and chronic kidney disease. In this paper, we review the current literature on the association between dietary oxalate intake and kidney outcomes.
Original languageEnglish
Pages (from-to)1-15
Number of pages15
Publication statusPublished - 2020


  • Acute kidney injury
  • Randomized Controlled Trials as Topic
  • Diet
  • Nephrocalcinosis
  • Nephrolithiasis
  • Oxalate
  • Animals
  • Disease Models, Animal
  • Glomerular Filtration Rate
  • Humans
  • Kidney
  • Oxalates
  • Chronic kidney disease


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