@article{3c3af44ce44e476aa4082eb94c1d5241,
title = "Decreased plasma levels of darunavir/ritonavir in a vertically infected pregnant woman carrying multiclass-resistant HIV type-1",
abstract = "We report a case of a vertically infected woman treated with darunavir/ritonavir plus a standard backbone before pregnancy. The analysis of darunavir/ritonavir concentrations in peripheral maternal plasma throughout pregnancy, as well as in umbilical cord blood at delivery, showed low levels of darunavir in the mother and limited transfer across the placenta.",
keywords = "Drug Resistance, Multiple, Viral, Drug Therapy, Combination, Female, Fetal Blood, HIV Infections, HIV Protease Inhibitors, HIV-1, Humans, Infant, Newborn, Infectious Disease Transmission, Vertical, Pregnancy, Pregnancy Complications, Infectious, RNA, Viral, Ritonavir, Sulfonamides, Young Adult, Drug Resistance, Multiple, Viral, Drug Therapy, Combination, Female, Fetal Blood, HIV Infections, HIV Protease Inhibitors, HIV-1, Humans, Infant, Newborn, Infectious Disease Transmission, Vertical, Pregnancy, Pregnancy Complications, Infectious, RNA, Viral, Ritonavir, Sulfonamides, Young Adult",
author = "Carmela Pinnetti and Enrica Tamburrini and Enzo Ragazzoni and {De Luca}, Andrea and Pierluigi Navarra",
year = "2010",
doi = "10.3851/IMP1473",
language = "English",
volume = "15",
pages = "127--129",
journal = "Antiviral Therapy",
issn = "1359-6535",
publisher = "International Medical Press:2-4 Idol Lane, London EC3R 5DD United Kingdom:011 44 207 3980700, EMAIL:
[email protected], INTERNET: http://www.intmedpress.com, Fax: 011 44 207 3980701",
}
