De novo expression of calretinin in trimethyltin-induced degeneration of developing rat hippocampus

Rita Businaro; Valentina Corvino; Maria Concetta Geloso; Elena De Santis; Lorenzo Fumagalli; Fabrizio Michetti

De novo expression of calretinin in trimethyltin-induced degeneration of developing rat hippocampus

Rita Businaro
, Valentina Corvino
, Maria Concetta Geloso
, Elena De Santis
, Lorenzo Fumagalli
, Fabrizio Michetti

Research output: Contribution to journal › Article › peer-review

Abstract

In the model of trimethyltin (TMT)-induced neurodegeneration in developing rat hippocampus, calretinin (CR)-immunoreactive neurons are selectively spared and even more numerous than in controls. We investigated the possibility of an additional synthesis of CR using RT-PCR. The amount of CR mRNA increased significantly after TMT treatment. CR mRNA production after TMT treatment could hypothetically be regarded as a compensatory phenomenon in developing rats.

Original language	English
Pages (from-to)	141-144
Number of pages	4
Journal	Molecular Brain Research
Publication status	Published - 2002

Keywords

Calretinin
Development
Neurodegeneration
Trimethyltin

Cite this

@article{3e9e39e207a84c2ea523950745c86e12,

title = "De novo expression of calretinin in trimethyltin-induced degeneration of developing rat hippocampus",

abstract = "In the model of trimethyltin (TMT)-induced neurodegeneration in developing rat hippocampus, calretinin (CR)-immunoreactive neurons are selectively spared and even more numerous than in controls. We investigated the possibility of an additional synthesis of CR using RT-PCR. The amount of CR mRNA increased significantly after TMT treatment. CR mRNA production after TMT treatment could hypothetically be regarded as a compensatory phenomenon in developing rats.",

keywords = "Calretinin, Development, Neurodegeneration, Trimethyltin, Calretinin, Development, Neurodegeneration, Trimethyltin",

author = "Rita Businaro and Valentina Corvino and Geloso, \{Maria Concetta\} and \{De Santis\}, Elena and Lorenzo Fumagalli and Fabrizio Michetti",

year = "2002",

language = "English",

pages = "141--144",

journal = "Molecular Brain Research",

issn = "0169-328X",

publisher = "Elsevier BV",

}

TY - JOUR

T1 - De novo expression of calretinin in trimethyltin-induced degeneration of developing rat hippocampus

AU - Businaro, Rita

AU - Corvino, Valentina

AU - Geloso, Maria Concetta

AU - De Santis, Elena

AU - Fumagalli, Lorenzo

AU - Michetti, Fabrizio

PY - 2002

Y1 - 2002

N2 - In the model of trimethyltin (TMT)-induced neurodegeneration in developing rat hippocampus, calretinin (CR)-immunoreactive neurons are selectively spared and even more numerous than in controls. We investigated the possibility of an additional synthesis of CR using RT-PCR. The amount of CR mRNA increased significantly after TMT treatment. CR mRNA production after TMT treatment could hypothetically be regarded as a compensatory phenomenon in developing rats.

AB - In the model of trimethyltin (TMT)-induced neurodegeneration in developing rat hippocampus, calretinin (CR)-immunoreactive neurons are selectively spared and even more numerous than in controls. We investigated the possibility of an additional synthesis of CR using RT-PCR. The amount of CR mRNA increased significantly after TMT treatment. CR mRNA production after TMT treatment could hypothetically be regarded as a compensatory phenomenon in developing rats.

KW - Calretinin

KW - Development

KW - Neurodegeneration

KW - Trimethyltin

KW - Calretinin

KW - Development

KW - Neurodegeneration

KW - Trimethyltin

UR - http://hdl.handle.net/10807/8200

M3 - Article

SN - 0169-328X

SP - 141

EP - 144

JO - Molecular Brain Research

JF - Molecular Brain Research

ER -

De novo expression of calretinin in trimethyltin-induced degeneration of developing rat hippocampus

Abstract

Keywords

Other files and links

Fingerprint

Cite this