Conjunctival melanoma is a rare primary ocular tumor. So far, no standard treatment exists formetastatic disease. Similarly to cutaneousmelanoma, up to 50%of conjunctival melanomas harbor BRAF mutations. The most common is represented by V600E. Combined therapy with BRAF and MEK inhibitors is approved for BRAF mutant cutaneous metastatic melanomas. Herein, we report a case of a 70-years old patient with a metastatic conjunctival melanoma harboring V600E BRAF mutation successfully treated with dabrafenib and trametinib.
Original languageEnglish
Pages (from-to)1-5
Number of pages5
JournalFrontiers in Oncology
Publication statusPublished - 2019


  • BRAF
  • conjunctival


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