Cytoplasmic expression of estrogen receptor beta (ERβ) predicts poor clinical outcome in advanced serous ovarian cancer

Gian Franco Zannoni, Anna Fagotti, Giovanni Scambia, Giuseppe Vizzielli, Daniela Gallo Guido, Ilaria De Stefano, Mg Prisco, L Tortorella, L Mencaglia

Research output: Contribution to journalArticle

51 Citations (Scopus)

Abstract

In this study we investigated the prognostic value of estrogen receptor α (ERα), ERβ and progesterone receptor (PR) expression in 58 untreated advanced serous ovarian cancer patients. The study also included 12 macroscopically and histopathologically normal ovaries.
Original languageEnglish
Pages (from-to)573-579
Number of pages7
JournalGynecologic Oncology
Volume122
DOIs
Publication statusPublished - 2011

Keywords

  • Adult
  • Aged
  • Antineoplastic Combined Chemotherapy Protocols
  • Carboplatin
  • Cell Nucleus
  • Cisplatin
  • Cohort Studies
  • Cystadenocarcinoma, Serous
  • Cytoplasm
  • Disease-Free Survival
  • Estrogen Receptor alpha
  • Estrogen Receptor beta
  • Female
  • Humans
  • Immunohistochemistry
  • Middle Aged
  • Ovarian Neoplasms
  • Paclitaxel
  • Receptors, Progesterone

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