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cytomorphology of chimeric antigen receptor T-Cells (CAR-T)

Research output: Contribution to journalArticle

Abstract

Chimeric antigen receptor (CAR) T cells represent one of the newest frontiers of cell therapy. Their application currently involves relapsed/refractory aggressive B cell lymphoma and leukemia as a standard of care, while several studies are exploring CAR-T to treat multiple myeloma and other hematological malignancies. Here we describe the cytomorphology of CAR-T collected from the leftovers of infusion bags, and therefore before the encounter with the antigen, with, among others, a peculiar population of giant lymphoid cells with blastoid features and hypertrophic centrosome.
Original languageEnglish
Pages (from-to)1-13
Number of pages13
JournalMediterranean Journal of Hematology and Infectious Diseases
Volume13
Issue number13
DOIs
Publication statusPublished - 2021

All Science Journal Classification (ASJC) codes

  • Hematology
  • Infectious Diseases

Keywords

  • cytomorphology of chimeric

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