Cryoablation in Locoregional Management of Complex Unresectable Chest Neoplasms

Roberto Iezzi, Andrea Contegiacomo, Alessandro Posa, Nico Attempati, Ernesto Punzi, Alessandro Tanzilli, Stefano Margaritora, Maria Teresa Congedo, Alessandra Cassano, Emilio Bria, Luca Tagliaferri, Vincenzo Valentini, Cesare Colosimo, Riccardo Manfredi

Research output: Contribution to journalArticle


Rationale and Objectives: The aim of our retrospective study was to assess the safety and feasibility of cryoablation in high-risk patients with complex chest neoplastic lesions. Materials and Methods: Twenty patients with complex chest malignancies, both primary and secondary, located in the mediastinum, lung, and chest wall, underwent percutaneous CT-guided cryoablation treatments. Procedural success as well as complications were evaluated. Results: A total of 24 neoplastic lesions were treated (mean diameter: 27 mm; range: 7-54 mm). Technical success was obtained in all patients, without major complications or intraprocedural death. A pneumothorax not requiring a drainage tube placement was registered in 50% of patients, while 3/24 patients had a grade 3 pneumothorax requiring a chest tube placement. Conclusion: Percutaneous CT-guided cryoablation seems a safe and feasible treatment for complex thoracic lesions.
Original languageEnglish
Pages (from-to)688-696
Number of pages9
Publication statusPublished - 2021


  • cryoablation
  • interventional radiology
  • lung tumors


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