Cost-effectiveness of colorectal cancer screening with computed tomography colonography: the impact of not reporting diminutive lesions

Pj Pickhardt, Cesare Hassan, A Laghi, A Zullo, Dh Kim, S. Morini

Research output: Contribution to journalArticle

164 Citations (Scopus)

Abstract

Prior cost-effectiveness models analyzing computed tomography colonography (CTC) screening have assumed that patients with diminutive lesions (<or=5 mm) will be referred to optical colonoscopy (OC) for polypectomy. However, consensus guidelines for CTC recommend reporting only polyps measuring >or=6 mm. The purpose of the current study was to assess the potential harms, benefits, and cost-effectiveness of CTC screening without the reporting of diminutive lesions compared with other screening strategies.
Original languageEnglish
Pages (from-to)2213-2221
Number of pages9
JournalCancer
Volume109
DOIs
Publication statusPublished - 2007
Externally publishedYes

Keywords

  • Aged
  • Aged, 80 and over
  • Colonic Polyps
  • Colonography, Computed Tomographic
  • Colonoscopy
  • Colorectal Neoplasms
  • Cost-Benefit Analysis
  • Humans
  • Italy
  • Mass Screening
  • Middle Aged
  • Sensitivity and Specificity
  • Sigmoidoscopy

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