Controversies in venous thromboembolism: the unique case of isolated distal deep vein thrombosis

Roberto Pola, Angelo Porfidia, Annamaria Carnicelli, Nicola Bonadia, Raffaele Landolfi

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)

Abstract

Venous thromboembolism (VTE) represents the third leading cause of cardiovascular mortality, and it is the main cause of preventable mortality in hospitalized patients. Among VTE, there is the unique case of isolated distal deep vein thrombosis (IDDVT), which still lacks an agreement in terms of optimal therapeutic strategy. Although most IDDVTs are self-limiting and associated with a very low risk of embolic complications, still not all IDDVTs can be safely identified as stable. Lack of strong scientific evidence, fear of thromboembolic complications, and risk of bleeding upon initiation of anticoagulant treatment result in very heterogeneous therapeutic strategies among physicians. Here, we provide a comprehensive review of the literature, highlight the many controversial issues regarding IDDVTs, and call for a consensus of experts aimed to shed new light on the gray areas of IDDVT management and therapy.
Original languageEnglish
Pages (from-to)N/A-N/A
JournalInternal and Emergency Medicine
DOIs
Publication statusPublished - 2016

Keywords

  • Anticoagulant
  • Calf thrombosis
  • IDDVT
  • Isolated distal deep vein thrombosis

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