Abstract
[Autom. eng. transl.] Recent models suggest that executive impairments may negatively contribute to the functional decline of patients with substance use disorder (DUS), aggravating their secondary affective and social symptoms. Despite these potential implications, the screening tools typically used to assess such impairments are not specific for the sequelae of addiction pictures and are unable to correctly delineate the dysfunctional executive control profile. This study concerns the development and validation of a new specific screening battery for neurocognitive disorders in addiction. The screening battery was tested on 151 patients with DUS and 55 control subjects. The battery consists of neuropsychological tests (focus: verbal and working memory, focused attention, cognitive flexibility) and computerized neurocognitive tasks (Stroop and Go / No-go tasks adapted for the evaluation of interference inhibition, executive control, and attentional bias towards drugs of abuse). Statistical analyzes showed worse cognitive performance in patients with DUS compared to controls, both in tests of cognitive flexibility, focused attention and verbal memory and in computerized tasks, suggesting the presence of a deficit of inhibitory mechanisms and regulation of attention and cognitive resources. . These results were also confirmed by second-level analyzes carried out by checking the modulator role of age and education, suggesting the robustness of the measures implemented. The results confirm the link between specific executive impairments and DUS and suggest the potential of the battery as a valid neurocognitive screening tool.
Translated title of the contribution | [Autom. eng. transl.] Impaired Executive Function in Substance Use Disorder: A New Neurocognitive Screening Battery |
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Original language | Italian |
Title of host publication | Atti del XXVI Congresso AIP Sezione Sperimentale |
Pages | 128 |
Number of pages | 1 |
Publication status | Published - 2020 |
Event | XXVI Congresso AIP Sezione Sperimentale - Virtuale Duration: 2 Sept 2020 → 4 Sept 2020 |
Conference
Conference | XXVI Congresso AIP Sezione Sperimentale |
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City | Virtuale |
Period | 2/9/20 → 4/9/20 |
Keywords
- Addiction
- Funzioni esecutive
- Screening neurocognitivo