Common variable immunodeficiency - new insight into the pathogenesis and the quest for a workable classification.

Rossella Cianci, Franco Pandolfi, Danilo Pagliari, Simona Frosali, C. Milito, V. Conti, I. Quinti

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

In this editorial we argue that more and more complex classifications for patients with common variable immunodeficiency (CVID) fail to identify those patients at high risk of developing infections. We propose that the minimal requirement to identify such patients is the absolute numbers of total and memory B cells and the IgM response to immunization with polysaccharides. If these data should be confirmed, they will provide the basis for a good classification of a heterogeneous group of patients. This simple, workable classification may result in a clinically useful identification of patients prone to more aggressive infections.
Original languageEnglish
Pages (from-to)285-289
Number of pages5
JournalJOURNAL OF BIOLOGICAL REGULATORS & HOMEOSTATIC AGENTS
Publication statusPublished - 2013

Keywords

  • Common variable immunodeficiency

Fingerprint

Dive into the research topics of 'Common variable immunodeficiency - new insight into the pathogenesis and the quest for a workable classification.'. Together they form a unique fingerprint.

Cite this