Colorviz, a new and rapid tool for assessing collateral circulation during stroke

Tommaso Verdolotti, Fabio Pilato, Simone Cottonaro, Edoardo Monelli, Carolina Giordano, Pamela Guadalupi, Massimo Benenati, Antonia Ramaglia, Alessandro Maria Costantini, Andrea Alexandre, Riccardo Di Iorio, Cesare Colosimo

Research output: Contribution to journalArticle

2 Citations (Scopus)


Prognosis of patients with acute ischemic stroke is strictly related to the patency and prominence of the collateral leptomeningeal pathways distal to the arterial occlusion. The gold standard for assessment of collateral circulation is conventional angiography, but it is invasive and used in selected cases. To date, the most reliable technique is multiphase CTA; currently, the available classifications of collateral circles are often complex, time-consuming, and require a trained observer. The purpose of our work is to establish the effectiveness of a new semi-automatic post-processing software (ColorViz FastStroke, GE Healthcare, Milwaukee, Wisconsin) in evaluation of collateral circulation compared to the six-point classifications of multiphase CTA already validated in literature. We selected 86 patients with anterior ischemic stroke symptoms who underwent multiphasic CTA in our emergency department. Two radiologists separately evaluated the collateral leptomeningeal vessels, analyzing respectively, the multiphase CTA (using the six-point scale and its trichotomized form) and ColorViz (using a three-point scale). Then the results were matched. We found a good correlation between the two different analyses; the main advantage of ColorViz is that, while maintaining fast diagnostic times, it allows a simpler and more immediate evaluation of collateral circulation, especially for less experienced radiologists.
Original languageEnglish
Pages (from-to)1-8
Number of pages8
JournalBrain Sciences
Publication statusPublished - 2020


  • Acute ischemic stroke
  • Collateral grading scales
  • Color Map
  • Leptomeningeal collaterals
  • Multiphase CT angiography


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