Collagen scaffold and lipoaspirate fluid - Derived stem cells for the treatment of cartilage defects in a Rabbit Model

Wanda Lattanzi, Maristella Francesca Saccomanno, Giuseppe Milano, Horea Rares Ciprian Benea, Kamel Earar, Cristian Berce, Olga Soritau, Gheorghe Tomoaia, Diana Cerchizan, Aurel Mohan

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

The purpose of the present study was to assess and compare the chondroregenerative properties of PLA (processed lipoaspirate) and LAF (lipoaspirate fluid) cells, in a preclinical rabbit model of knee cartilage defect. The defects were repaired by a collagen I/III scaffold and added LAF-cells, PLA-cells or no cells, upon the study group. The results showed that collagen scaffolds seeded with LAF-derived stem cells appear to have slightly better activity and outcomes when compared to PLA-cells, in terms of cartilage regeneration.
Original languageEnglish
Pages (from-to)515-520
Number of pages6
JournalRevista de Chimie
Volume69
DOIs
Publication statusPublished - 2018

Keywords

  • Cartilage
  • Collagen
  • Regeneration
  • Scaffold
  • Stem cells

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