Cocaine abuse in pregnancy: Its evaluation through hair analysis of pathological new-borns

Sabina Strano Rossi; Marcello Chiarotti; A Fiori; C Auriti; G. Seganti

doi:10.1016/S0024-3205(96)00538-3

Cocaine abuse in pregnancy: Its evaluation through hair analysis of pathological new-borns

Sabina Strano Rossi, Marcello Chiarotti, A Fiori, C Auriti, G. Seganti

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

Cocaine abuse in pregnancy has been evaluated through toxicological analysis of hair from 123 pathological new-barns admitted in an intensive care division. The newborns were affected with malformations, low gestational age, low birth weight, respiratory distress. A control group of 39 healthy new-boms was also analysed. Hair samples (about 50 mg) were enzymatically digested and directly analysed by RIA. Samples positive to the preliminary screening were extracted by SPE columns and injected in GCNS. Results obtained showed 3 positive samples (2.4%). All cocaine babies had low gestational age, low birth weight, two of them showed heart malformation, one kidney malformation and one genital malformation. None of the control new-born resulted positive for cocaine. These results show a worrying trend of cocaine diffusion in the Italian population.

Original language	English
Pages (from-to)	1909-1915
Number of pages	7
Journal	Life Sciences
Volume	59
DOIs	https://doi.org/10.1016/S0024-3205(96)00538-3
Publication status	Published - 1996

Keywords

cocaine
hair analysis
pathological newborns

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10.1016/S0024-3205(96)00538-3

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title = "Cocaine abuse in pregnancy: Its evaluation through hair analysis of pathological new-borns",

abstract = "Cocaine abuse in pregnancy has been evaluated through toxicological analysis of hair from 123 pathological new-barns admitted in an intensive care division. The newborns were affected with malformations, low gestational age, low birth weight, respiratory distress. A control group of 39 healthy new-boms was also analysed. Hair samples (about 50 mg) were enzymatically digested and directly analysed by RIA. Samples positive to the preliminary screening were extracted by SPE columns and injected in GCNS. Results obtained showed 3 positive samples (2.4%). All cocaine babies had low gestational age, low birth weight, two of them showed heart malformation, one kidney malformation and one genital malformation. None of the control new-born resulted positive for cocaine. These results show a worrying trend of cocaine diffusion in the Italian population.",

keywords = "cocaine, hair analysis, pathological newborns, cocaine, hair analysis, pathological newborns",

author = "{Strano Rossi}, Sabina and Marcello Chiarotti and A Fiori and C Auriti and G. Seganti",

year = "1996",

doi = "10.1016/S0024-3205(96)00538-3",

language = "English",

volume = "59",

pages = "1909--1915",

journal = "Life Sciences",

issn = "0024-3205",

publisher = "Elsevier Inc.",

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TY - JOUR

T1 - Cocaine abuse in pregnancy: Its evaluation through hair analysis of pathological new-borns

AU - Strano Rossi, Sabina

AU - Chiarotti, Marcello

AU - Fiori, A

AU - Auriti, C

AU - Seganti, G.

PY - 1996

Y1 - 1996

N2 - Cocaine abuse in pregnancy has been evaluated through toxicological analysis of hair from 123 pathological new-barns admitted in an intensive care division. The newborns were affected with malformations, low gestational age, low birth weight, respiratory distress. A control group of 39 healthy new-boms was also analysed. Hair samples (about 50 mg) were enzymatically digested and directly analysed by RIA. Samples positive to the preliminary screening were extracted by SPE columns and injected in GCNS. Results obtained showed 3 positive samples (2.4%). All cocaine babies had low gestational age, low birth weight, two of them showed heart malformation, one kidney malformation and one genital malformation. None of the control new-born resulted positive for cocaine. These results show a worrying trend of cocaine diffusion in the Italian population.

AB - Cocaine abuse in pregnancy has been evaluated through toxicological analysis of hair from 123 pathological new-barns admitted in an intensive care division. The newborns were affected with malformations, low gestational age, low birth weight, respiratory distress. A control group of 39 healthy new-boms was also analysed. Hair samples (about 50 mg) were enzymatically digested and directly analysed by RIA. Samples positive to the preliminary screening were extracted by SPE columns and injected in GCNS. Results obtained showed 3 positive samples (2.4%). All cocaine babies had low gestational age, low birth weight, two of them showed heart malformation, one kidney malformation and one genital malformation. None of the control new-born resulted positive for cocaine. These results show a worrying trend of cocaine diffusion in the Italian population.

KW - cocaine

KW - hair analysis

KW - pathological newborns

KW - cocaine

KW - hair analysis

KW - pathological newborns

UR - http://hdl.handle.net/10807/31098

UR - http://dx.medra.org/10.1016/s0024-3205(96)00538-3

U2 - 10.1016/S0024-3205(96)00538-3

DO - 10.1016/S0024-3205(96)00538-3

M3 - Article

SN - 0024-3205

VL - 59

SP - 1909

EP - 1915

JO - Life Sciences

JF - Life Sciences

ER -

Cocaine abuse in pregnancy: Its evaluation through hair analysis of pathological new-borns

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Keywords

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