Clinical use of plasma chitotriosidase in severe sepsis

Carlo Chiarla, Ivo Giovannini*, Daniela Antuzzi, Andrea Piras, Francesco Ardito, Felice Giuliante

*Corresponding author

Research output: Contribution to journalArticle

2 Citations (Scopus)


Plasma chitotriosidase activity (ChT) was previously proposed to quantify severity of sepsis. In a complex surgical case, with prolonged sepsis and consistently high ChT, we found that the least increased values occurred in stages of extreme illness, with profound hypocholesterolemia. ChT needs better characterization before becoming a reliable biomarker of septic evolution.
Original languageEnglish
Pages (from-to)273-276
Number of pages4
JournalCurrent Medical Research and Opinion
Publication statusPublished - 2016


  • Aged
  • Biomarkers
  • Critical illness
  • Hexosaminidases
  • Humans
  • Hypocholesterolemia
  • Intensive care
  • Male
  • Medicine (all)
  • Monitoring
  • Plasma chitotriosidase
  • Sepsis


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