Chronic subdural hematoma in patients aged 80 years and older: A two-centre study

Mariaconsiglia Santantonio, Giuseppe Trevisi, Carmelo Anile, Annunziato Mangiola, Pasquale De Bonis, Simone Olei, Lorenzo Mongardi, Michele Alessandro Cavallo

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14 Citations (Scopus)


Objective: Chronic subdural hematoma (CSDH) is a common condition in the elderly, and the ageing of population will increase the number of "superaged" patients presenting this pathology for the years to come. Few studies investigating the outcome of superaged patients surgically treated for CSDH are available, and study populations are generally small. The outcome of surgically treated patients and risk factors are not completely clear.Aim of the work is to identify the risk factors which may influence the outcome of patients aged 80 years and older surgically treated for CSDH.Patients and Methods: This is a retrospective two-centre study including 151 surgically treated patients. A univariate (Fisher exact test) and multivariate (logistic regression) analysis of possible risk factors influencing outcome was performed. Outcome was expressed as: 6-month clinical outcome, 6-month mortality, complications and length of hospital stay.Results: Univariate analysis showed an association between Charlson Comorbidity Index (CCI) and 6-month clinical outcome (p = 0,048), complications (p = 0,034) and 6-month mortality (p = 0,007). Antithrombotic drugs were associated with longer hospital stay (p < 0,001). Logistic regression analysis showed an association between CCI and complications (p = 0,016, HR = 3,18) and 6-month mortality (p = 0,034, HR = 11,71), and between antithrombotic drugs and longer hospital stay (p = 0,002, HR = 3,07).Conclusions: Age alone is not a predictor of bad outcome for patients aged 80 years and older surgically treated for CSDH. Charlson Comorbidity Index (CCI) may prove a valuable outcome predicting tool in these patients, and a longer hospital stay may be anticipated for patients under antithrombotic agents.
Original languageEnglish
Pages (from-to)88-92
Number of pages5
JournalClinical Neurology and Neurosurgery
Publication statusPublished - 2018


  • Anticoagulant therapy
  • Antiplatelet therapy
  • Charlson comorbidity index
  • Chronic subdural hematoma
  • Elderly patients
  • Surgery


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