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Cardiopulmonary bypass in man: role of the intestine in a self-limiting inflammatory response with demonstrable bacterial translocation

  • Marianna Rossi*
  • , Gabriele Sganga
  • , Marinella Mazzone
  • , Venanzio Valenza
  • , Sergio Guarneri
  • , G Portale
  • , Lorenzo Carbone
  • , L Gatta
  • , C Pioli
  • , Maurizio Sanguinetti
  • , Massimo Montalto
  • , Franco Glieca
  • , Giovanni Fadda
  • , Rocco Schiavello
  • , Ng Silveri
  • *Corresponding author

Research output: Contribution to journalArticle

Abstract

Cardiopulmonary bypass provokes a systemic inflammatory reaction that, in 1% to 2% of all cases, leads to multiorgan disfunction. The aim of this study was to evaluate the possible role of the intestine in the pathogenesis and development of this reaction.
Original languageEnglish
Pages (from-to)612-618
Number of pages7
JournalAnnals of Thoracic Surgery
Volume77
Issue number2
DOIs
Publication statusPublished - 2004

All Science Journal Classification (ASJC) codes

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

Keywords

  • Adult
  • Aged
  • Bacteremia
  • Bacterial Translocation
  • Cardiopulmonary Bypass
  • Coronary Artery Bypass
  • Coronary Disease
  • Cytokines
  • Escherichia coli
  • Escherichia coli Infections
  • Female
  • Gastric Mucosa
  • Humans
  • Intestinal Absorption
  • Intestinal Mucosa
  • Male
  • Middle Aged
  • NF-kappa B
  • Postoperative Complications
  • Prospective Studies
  • Risk Factors
  • Systemic Inflammatory Response Syndrome

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