Cardiac Rehabilitation and Endothelial Function

Gaetano Antonio Lanza, Augusto Fusco, Michele Golino, Angelo Villano, Oreste Lanza, Priscilla Lamendola, Massimo Leggio

Research output: Contribution to journalArticle


Endothelial dysfunction is an early abnormality in the process of atherosclerosis and cardiovascular disease and has been associated with worse clinical outcome. Cardiac rehabilitation (CR) has been reported to be helpful to reduce cardiovascular events in various types of cardiac disease, but the mechanisms of its beneficial effects remain only partially known. In this article, we review the studies that assessed the effect of CR on endothelial function in patients with various cardiac conditions. Available data show that CR significantly improves impaired endothelial function in these patients, which may contribute to the beneficial effects of CR on clinical outcome.
Original languageEnglish
Pages (from-to)2487-N/A
JournalJournal of Clinical Medicine
Publication statusPublished - 2020


  • cardiac rehabilitation
  • clinical outcome
  • endothelial function


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