Cardiac Imaging in Childhood Cancer Survivors: A State-of-the-Art Review

Massimiliano Camilli, Roderick Skinner, Giulia Iannaccone, Giulia La Vecchia, Rocco Antonio Montone, Gaetano Antonio Lanza, Luigi Natale, Filippo Crea, Matteo Cameli, Marco Giuseppe Del Buono, Antonella Lombardo, Giorgio Minotti

Research output: Contribution to journalArticle


Childhood cancer survival has improved significantly in the past few decades, reaching rates of 80% or more at 5 years. However, with improved sur-vival, early-and late-occurring complications of che-motherapy and radiotherapy exposure are becoming progressively more evident. Cardiovascular diseases represent the leading cause of non-oncological morbid-ity and mortality in this highly vulnerable population. Therefore, the necessity of reliable, noninvasive screening tools able to early identify cardiac complica-tions early is now pre-eminent in order to implement prevention strategies and mitigate disease progression. Echocardiography, may allow identification of myo-cardial dysfunction, pericardial complications, and valvular heart diseases. However, additional imaging modalities may be necessary in selected cases. This manuscript provides an in-depth review of noninvasive imaging parameters studied in childhood cancer survi-vors. Furthermore, we will illustrate brief surveillance recommendations according to available evidence and future perspectives in this expanding field. (Curr Probl Cardiol 2023;48:101544.)
Original languageEnglish
Pages (from-to)48-55
Number of pages8
JournalCurrent Problems in Cardiology
Publication statusPublished - 2023


  • Cardiac


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