Cancer stem cell analysis and clinical outcome in patients with glioblastoma multiforme

Roberto Pallini; Lucia Ricci Vitiani; Giuseppe Luigi Banna; Michele Signore; Dario Lombardi; Matilde Todaro; Giorgio Stassi; Maurizio Martini; Giulio Maira; Luigi Maria Larocca; Ruggero De Maria

doi:10.1158/1078-0432.CCR-08-0644

Cancer stem cell analysis and clinical outcome in patients with glioblastoma multiforme

Roberto Pallini
, Lucia Ricci Vitiani
, Giuseppe Luigi Banna
, Michele Signore
, Dario Lombardi
, Matilde Todaro
, Giorgio Stassi
, Maurizio Martini
, Giulio Maira
, Luigi Maria Larocca
, Ruggero De Maria

Università Cattolica del Sacro Cuore

Research output: Contribution to journal › Article

266 Citations (Scopus)

Abstract

Cancer stem cells (CSC) are thought to represent the population of tumorigenic cells responsible for tumor development. The stem cell antigen CD133 identifies such a tumorigenic population in a subset of glioblastoma patients. We conducted a prospective study to explore the prognostic potential of CSC analysis in glioblastoma patients.

Original language	English
Pages (from-to)	8205-8212
Number of pages	8
Journal	Clinical Cancer Research
Volume	14
DOIs	https://doi.org/10.1158/1078-0432.CCR-08-0644
Publication status	Published - 2008

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Adult
Aged
Antigens, CD
Brain Neoplasms
Female
Glioblastoma
Glycoproteins
Humans
Ki-67 Antigen
Male
Middle Aged
Multivariate Analysis
Neoplastic Stem Cells
Peptides
Prospective Studies

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10.1158/1078-0432.CCR-08-0644

Cite this

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title = "Cancer stem cell analysis and clinical outcome in patients with glioblastoma multiforme",

abstract = "Cancer stem cells (CSC) are thought to represent the population of tumorigenic cells responsible for tumor development. The stem cell antigen CD133 identifies such a tumorigenic population in a subset of glioblastoma patients. We conducted a prospective study to explore the prognostic potential of CSC analysis in glioblastoma patients.",

keywords = "Adult, Aged, Antigens, CD, Brain Neoplasms, Female, Glioblastoma, Glycoproteins, Humans, Ki-67 Antigen, Male, Middle Aged, Multivariate Analysis, Neoplastic Stem Cells, Peptides, Prospective Studies, Adult, Aged, Antigens, CD, Brain Neoplasms, Female, Glioblastoma, Glycoproteins, Humans, Ki-67 Antigen, Male, Middle Aged, Multivariate Analysis, Neoplastic Stem Cells, Peptides, Prospective Studies",

author = "Roberto Pallini and \{Ricci Vitiani\}, Lucia and Banna, \{Giuseppe Luigi\} and Michele Signore and Dario Lombardi and Matilde Todaro and Giorgio Stassi and Maurizio Martini and Giulio Maira and Larocca, \{Luigi Maria\} and \{De Maria\}, Ruggero",

year = "2008",

doi = "10.1158/1078-0432.CCR-08-0644",

language = "English",

volume = "14",

pages = "8205--8212",

journal = "Clinical Cancer Research",

issn = "1078-0432",

publisher = "American Association for Cancer Research Inc.",

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TY - JOUR

T1 - Cancer stem cell analysis and clinical outcome in patients with glioblastoma multiforme

AU - Pallini, Roberto

AU - Ricci Vitiani, Lucia

AU - Banna, Giuseppe Luigi

AU - Signore, Michele

AU - Lombardi, Dario

AU - Todaro, Matilde

AU - Stassi, Giorgio

AU - Martini, Maurizio

AU - Maira, Giulio

AU - Larocca, Luigi Maria

AU - De Maria, Ruggero

PY - 2008

Y1 - 2008

N2 - Cancer stem cells (CSC) are thought to represent the population of tumorigenic cells responsible for tumor development. The stem cell antigen CD133 identifies such a tumorigenic population in a subset of glioblastoma patients. We conducted a prospective study to explore the prognostic potential of CSC analysis in glioblastoma patients.

AB - Cancer stem cells (CSC) are thought to represent the population of tumorigenic cells responsible for tumor development. The stem cell antigen CD133 identifies such a tumorigenic population in a subset of glioblastoma patients. We conducted a prospective study to explore the prognostic potential of CSC analysis in glioblastoma patients.

KW - Adult

KW - Aged

KW - Antigens, CD

KW - Brain Neoplasms

KW - Female

KW - Glioblastoma

KW - Glycoproteins

KW - Humans

KW - Ki-67 Antigen

KW - Male

KW - Middle Aged

KW - Multivariate Analysis

KW - Neoplastic Stem Cells

KW - Peptides

KW - Prospective Studies

KW - Adult

KW - Aged

KW - Antigens, CD

KW - Brain Neoplasms

KW - Female

KW - Glioblastoma

KW - Glycoproteins

KW - Humans

KW - Ki-67 Antigen

KW - Male

KW - Middle Aged

KW - Multivariate Analysis

KW - Neoplastic Stem Cells

KW - Peptides

KW - Prospective Studies

UR - http://hdl.handle.net/10807/26202

U2 - 10.1158/1078-0432.CCR-08-0644

DO - 10.1158/1078-0432.CCR-08-0644

M3 - Article

SN - 1078-0432

VL - 14

SP - 8205

EP - 8212

JO - Clinical Cancer Research

JF - Clinical Cancer Research

ER -

Cancer stem cell analysis and clinical outcome in patients with glioblastoma multiforme

Abstract

UN SDGs

Keywords

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