Caloric restriction and L-carnitine administration improves insulin sensitivity in patients with impaired glucose metabolism

Caterina Conte, A Molfino, A Cascino, C Ramaccini, F Rossi Fanelli, A. Laviano

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

Reduced circulating and tissue carnitine levels, possibly leading to impaired mitochondrial function, have been postulated to be involved in the pathogenesis of insulin resistance. However, whether L-carnitine administration may improve insulin sensitivity in patients with impaired fasting glucose (IFG) or type 2 diabetes mellitus (DM-2) is still controversial. The aim of the study was to explore the role of L-carnitine supplementation in influencing insulin sensitivity.
Original languageEnglish
Pages (from-to)295-299
Number of pages5
JournalJPEN. JOURNAL OF PARENTERAL AND ENTERAL NUTRITION
Volume34
DOIs
Publication statusPublished - 2010

Keywords

  • Aged
  • Aged, 80 and over
  • Blood Glucose
  • Caloric Restriction
  • Carnitine
  • Diabetes Mellitus, Type 2
  • Female
  • Glucose Intolerance
  • Glucose Metabolism Disorders
  • Glucose Tolerance Test
  • Humans
  • Insulin
  • Insulin Resistance
  • Male
  • Middle Aged

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