Gabriella Colicchio, Domenico Policicchio

Research output: Chapter in Book/Report/Conference proceedingChapter


Corpus callosotomy is a reasonably safe and effective palliative surgical procedure for some patients with intractable seizures who are not amenable to focal resection, it does not pretend to suppress seizures, but it aims at alleviating them, by reducing their severity [13, 14, 15]. This is a feasible and costeffective treatment for some patients, even those in developing countries and with limited resources [19]. It is useful for seizure control in adult and in children, particularly in children with catastrophic epilepsy syndromes. Lennox-Gastaut syndrome is the most common one and the result of seizure control is significant. Severe mental retardation is not a contraindication to perform callosotomy. As a reguard seizure type generalized seizures with fall (Drop-Attack) are the most responsive to callosotomy. Seizure control , when obtained, is stable over time [13]. Improved seizure control after callostomy is always associated with improved QOL, satisfaction of parents to the operation, and also satisfaction of family QOL. Significant neuropsychological deficits are evident only on formal testing, are usually ignored by patients/family members, and rarely cause impact on daily life.
Original languageEnglish
Title of host publicationHandbook of stereotactic and functional neurosurgery
Number of pages10
Publication statusPublished - 2011
Externally publishedYes


  • Epilepsy

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